Santa Fe is a fourth income class municipality in the province of Cebu Province, Philippines. According to the 2010 census, it has a population of 27,270. In the last election, it had 15,682 registered voters.
The municipality's territory occupies the southeastern portion of Bantayan Island (marching with the municipality of Bantayan), together with the islands of Guintacan (or Kinatarkan), Hilantagaan and Hilantagaan Diot. Because the island's airport and principal ferry port are both located within the municipality, Santa Fe is considered the gateway to Bantayan and its islands.
Although there is some small-scale industry, the municipality's principal source of income is fishing and agriculture, and from holidaymakers who come in large numbers, most notably during Holy Week, to enjoy the particularly fine white sand and uncrowded beaches.