Sappinia is a genus of Amoebozoa. Sappinia is a free-living amoeba (a single-celled organism), found in the environment. There are two known species of Sappinia: Sappinia diploidea and Sappinia pedata. Sappinia can cause a disease similar to GAE, However only one case of GAE due to Sappinia infection has ever been reported. In 1998, a healthy 38-year-old man from Texas was found to be infected with Sappinia pedata. Although the patient was hospitalized, he survived without any long-term consequences.
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^Wylezich, C.; Walochnik, J.; Michel, R. (2009). "High genetic diversity of Sappinia-like strains (Amoebozoa, Thecamoebidae) revealed by SSU rRNA investigations". Parasitology research105 (3): 869–873. doi:10.1007/s00436-009-1482-1. PMID19495795.