Sarfaraz K. Niazi

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Sarfaraz K. Niazi
سرفراز خان نیازی
Born (1949-07-10) 10 July 1949 (age 70)
Lucknow, Uttar Pradesh, India
ResidenceChicago, IL, US
NationalityUnited States,
Alma materUniversity of Illinois, Washington State University, and Karachi University.
Known forBiopharmaceuticals
AwardsSitara-i-Imtiaz (2012)
Inductee, Chicago Hall of Entrepreneurs (2015)[1]
Scientific career
FieldsPharmaceutical sciences
Recombinant manufacturing
InstitutionsUniversity of Illinois at Chicago
Aga Khan University Hospital
Higher Education Commission of Pakistan
University of Houston College of Pharmacy

Sarfaraz Khan Niazi (Urdu: سرفراز خان نیازی) was born in Lucknow, India in 1949; he migrated to Karachi, Pakistan in 1962, and to the United States in 1970. He is an expert in biopharmaceutical manufacturing and has worked in academia and in industry, and as an entrepreneur. He has written books in the field of pharmaceutical sciences, biotechnology, consumer healthcare and poetry. He has translated ghazals (love poems) of the Urdu poet Ghalib.[2]

Personal life[edit]

Niazi was born 10 July 1949 in Lucknow in India, and moved to Karachi with his parents in 1962.[3] His father was Niaz Fatehpuri, a scholar of religion and literature in Pakistan and India.[4]


Niazi earned a bachelor of science degree in pharmacy from the University of Karachi in 1969. In 1970 he moved to the United States. He obtained his master of science degree in pharmaceutical sciences in 1971 from Washington State University in Pullman, WA, and then moved to Illinois. In 1974, he obtained his doctorate in pharmaceutical sciences from the University of Illinois at Chicago.[3]


From 1972 to 1988, he taught at the College of Pharmacy at the University of Illinois at Chicago [5], and continues to serve as Adjunct Professor of Biopharmaceutical Sciences. From 1988 to 1996 he worked for Abbott Laboratories as its director of technical affairs [5] and at the same time, he was professor of pharmacology at the Aga Khan University Hospital in Karachi.[5]. In 1997, he established his own consulting business, known as Pharmaceutical Scientist, Inc.[6][5] In 2003 he founded Therapeutic Proteins, Inc. to develop biosimilar versions of biopharmaceuticals, such as filgrastim, erythropoietin, interferon, Pegfilgrastim, adalimumab, and other monoclonal antibodies. In March 2012, this company became Therapeutic Proteins International, LLC. The company has proprietary single-use bioreactor systems.[7][8] In November 2016, the company changed its name to Adello Biologics.[9]; in January 2019, Adello Biologics assets were purchased by Kasha Bioscience[10]. In 2018, Niazi went on to establish another start up in biopharmaceuticals called Karyo Biologics.[11][12]

Honorary Teaching[edit]

Since 2012, he has served as Adjunct Professor at the College of Pharmacy, University of Illinois. Since 2004, he has served as an adjunct professor at the University of Houston College of Pharmacy, and since 2007 as an adjunct professor at the HEJ Research Institute of Chemistry at the University of Karachi. Since 2013, he has been a NUST Visiting Professor at the National University of Sciences and Technology (NUST) in Islamabad, Pakistan.[10]


In 2002 Niazi published the first complete translation[13] of the ghazals of Mirza Asadullah Baig Khan, known as "Ghalib"[14] and another in 2009.[15] Niazi hosts a show on Voice of America every Sunday, where he recites ghazals.[16]


Niazi has published over 100 research articles [17][18] He is creator of variable volume distribution model to study safety and efficacy of drugs [19][20][21]


Niazi has challenged FDA guidance through three Citizen Petitions[22] [23][24]that urge FDA to rationalize testing to allow faster entry of generic drugs and biosimilars to the market. In response to Niazi Citizen Petition, the FDA withdrew a pivotal guidance for the approval of biosimilars[25].


On 14 August 2012, the Government of Pakistan announced that President Asif Ali Zardari awarded the Sitara-i-Imtiaz in Engineering Science to Sarfaraz.[26] In March 2015, he received Alum of the Year Award from the University of Illinois.[27] In September 2015, he was inducted into Chicago Entrepreneur Hall of Fame.[1]

Textbooks and professional handbooks[edit]

Niazi has 198 ISBNs assigned to his books;[28] Niazi's textbooks are generally made available royalty-free in the developing world.[29]

  • Textbook of Clinical Pharmacokinetics and Biopharmaceutics. Bsp Publications, 2010. ISBN 9789381075043.
  • Handbook of Pharmaceutical Manufacturing Formulations Volumes 1–6 Boca Raton, Florida: CRC, 2004. ISBN 9780849317521.
  • Handbook of Biogeneric Therapeutic Proteins: Regulatory, Manufacturing, Testing, and Patent Issues. Boca Raton, Florida: CRC, 2002. ISBN 9780849329913.
  • Handbook of Preformulation: Drugs, Botanicals and Biological Pharmaceutical Products. Boca Raton, Florida: CRC, 2006. ISBN 9780849371936.
  • Handbook of Bioequivalence Testing. Boca Raton, Florida: CRC, 2007. ISBN 9781482226379.


  1. ^ a b
  2. ^ "About the Ghazals - A Desertful of Roses".
  3. ^ a b Express News, Pakistan. 2 Oct 2014 ڈاکٹر سرفراز خان نیازی ؛ دنیائے طب میں انقلاب لانے والے پاکستانی سائنس دان English version via Google translate
  4. ^ Sarfaraz K. Niazi. Love Sonnets of Ghalib. Rupa & Co. (10 January 2009) ISBN 978-8171675968, see back flap.
  5. ^ a b c d
  6. ^ "".
  7. ^ Kristen Schorsch for Crains Chicago Business. 29 May 2014 Medicine or food? Both, is this startup's mission
  8. ^ Kate MacArthur, Special to Blue Sky in the Chicago Tribune. 17 June 2014, Q&A: How an inventor's trying to cut the cost of making biological drugs
  9. ^ LLC, Adello Biologics. "Therapeutic Proteins International Renames Company to Adello Biologics, LLC; Relocates Corporate Headquarters to Piscataway, New Jersey".
  10. ^ a b "Kashiv Pharma Acquires Adello Biologics and Becomes Kashiv BioSciences". 3 January 2019.
  11. ^ "Karyo Biologics, LLC". Karyo Biologics, LLC.
  12. ^ "Sarfaraz K. Niazi • BioTech Pharma Summit: Conference Series".
  13. ^ "Love Sonnets of Ghalib".
  14. ^ Gulzar for India Today. 25 February 2002 Ghalib in love. Book review: Love Sonnets of Ghalib, translated by Sarfaraz K. Niazi
  15. ^ Jamaluddin Aali, quoted in Sarfaraz K. Niazi. Wine of Passion. Lahore, Pakistan: Ferozsons Publishing, 2009
  16. ^ Nicole Fisher for Forbes. 30 August 2014 The Most Interesting Man Revolutionizing The Health World
  17. ^ "niazi s - PubMed - NCBI".
  18. ^ "Google Scholar".
  19. ^ "Variable volume pharmacokinetic models". 13 June 2017 – via Wikipedia.
  20. ^
  21. ^ "distribution volume niazi s - PubMed - NCBI".
  22. ^ "".
  23. ^ "".
  24. ^ "".
  25. ^ Fisher, Nicole. "Scientist Invented A New Pathway To Approve Biosimilars, And The FDA Is Listening". Forbes.
  26. ^ "President confers civil awards". The News. 14 August 2012.
  27. ^
  28. ^ [1] Page accessed 2 Feb 2016
  29. ^ University of Illinois College of Pharmacy National Advisory Board: Profile of Sarfaraz K. Niazi Page accessed 23 April 2015

External links[edit]