Born in Ōmi Province, Sasaki Takauji served the regent Hōjō Takatoki briefly, before aiding the shōgun Ashikaga Takauji in overthrowing the Kenmu Restoration (in which the Emperor Go-Daigo sought to regain real power) and establishing the Ashikaga shogunate. During his period of service to the shogunate, Sasaki Takauji served as shugo (military governor) of six provinces, and held a number of other important positions. He was also known for his waka and renga poetry, and contributed 81 of his poems to the first imperial anthology of renga, the Tsukubashū. He is portrayed in the epic Taiheiki as a paragon of elegance and luxury, and as the quintessential military aristocrat. He exemplifies the extreme of extravagant taste known as "basara" where "the love of the extraordinary and accumulation of objects was paramount", and hosted events such as the twenty-day-long flower viewing event at Oharano.
- Foster Father: Sasaki Sadamune (1287-1305)
- Father: Sasaki Muneuji
- Mother: Sasaki Munetsuna’s daughter
- Wife: Nikaido Tokitsuna’s daughter
- Sasaki Hidetsuna (d.1353)
- Sasaki Hidemune by Nikaido Tokitsuna’s daughter
- Sasaki Takahide (1328-1391) by Nikaido Tokitsuna’s daughter
- daughter married Akamatsu Norisuke
- daughter married Shiba ujiyori
- daughter married Rokkaku Ujiyori
- "Sasaki Takauji." (1985). Kodansha Encyclopedia of Japan, Tokyo: Kodansha Ltd.
- Renga by Sasaki Dōyo: Selected from the Tsukubashū (Tsukuba Anthology), tr. by K. Selden, Japan Focus 14, 14, 6 (15 July 2016)