Saville reaction

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The Saville reaction is a chemical reaction in which mercury replaces a nitrosyl from a thiol group.

It is used as a method of replacing the nitrosyl from the modified cysteines and thus can serve in research of the redox modification of different proteins.[1]


  1. ^ A scheme for the colorimetric determination of microgram amounts of thiols; Saville B. Analyst 83, 670 (1958) PN50818.

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