The building was originally a hunting lodge. It was refashioned by the architect Johann Lucas von Hildebrandt. Empress Maria Theresa had it enlarged in 1743 by Nicolò Pacassi for her mother, Empress Elizabeth Christine, who lived here from 1743 until her death in 1750. A prominent feature of the palace is the entrance hall.
The youngest daughter of Emperor Francis II, Archduchess Maria Anna, lived here from 1835 until her death in 1858. She is said to have been mentally retarded and to have suffered from a hideous facial deformity.
It was at Hetzendorf that future Empress Zita gave birth to her daughter, Archduchess Adelheid of Austria, in 1914. Adelheid was the second child of Empress Zita and future Emperor Charles I of Austria.
Today it houses a fashion school.
Media related to Schloss Hetzendorf at Wikimedia Commons