Schradan

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Schradan
Schradan.svg
Names
IUPAC name
N,N,N′,N′,N′′,N′′,N′′′,N′′′-Octamethyldiphosphoric tetraamide
Other names
OMPA, Octamethyl pyrophosphoramide
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.005.275
EC Number 205-801-0
KEGG
RTECS number UX5950000
UNII
UN number 3018
Properties
C8H24N4O3P2
Molar mass 286.253 g·mol−1
Density 1.09
Hazards
Main hazards Toxic
GHS pictograms The skull-and-crossbones pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS)The health hazard pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS)
GHS signal word Danger
H300, H310, H330, H371, H373, H402, H412
P260, P262, P264, P270, P271, P273, P280, P284, P301+310, P302+350, P304+340, P309+311, P310, P314, P320, P321, P322, P330, P361, P363, P403+233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Schradan, named after Gerhard Schrader, is an obsolete organophosphate insecticide.[1] Schradan itself is a weak cholinesterase inhibitor and requires metabolic activation to become active.[2]

See also[edit]

References[edit]

  1. ^ GARDINER, JE; KILBY, BA (April 1952). "Biochemistry of organic phosphorus insecticides. I. The mammalian metabolism of bis(dimethylamino) phosphonous anhydride (Schradan)". The Biochemical Journal. 51 (1): 78–85. PMC 1197790. PMID 14944535.
  2. ^ DAVISON, AN (October 1955). "The conversion of schra dan (OMPA) and parathion into inhibitors of cholinesterase by mammalian liver". The Biochemical Journal. 61 (2): 203–9. PMC 1215773. PMID 13260199.