At the end of the 2005 season, Camporeale left Carlton, following his desire for a three-year contract, when Carlton would only offer a two-year contract. Carlton tried to make it difficult for him to leave, so Camporeale nominated for the 2006 Pre-season Draft. Essendon drafted Camporeale with draft pick number four in the pre-season draft. 
Camporeale debuted with Essendon in Round One, 2006. His career came to an end when he suffered a right knee injury in Round 21 2007. It occurred when he changed direction to tackle an opponent resulting with his knee bending and twisting the wrong way. He had successful ACL surgery on the knee but at 32 he opted to retire. He played 19 games for the Bombers in two seasons.
Following the death of Phil Walsh, Camporeale was appointed interim coach to the end of the 2015 season. Despite coaching the Crows to seven wins from his eleven matches in charge, he chose not to apply for the role full-time, with Don Pyke instead named Walsh's permanent successor.