About 47 AD, at the request of Gaius Julius Callistus, the emperor's freedman, he drew up a list of 271 prescriptions (Compositiones), most of them his own, although he acknowledged his indebtedness to his tutors, to friends, and to the writings of eminent physicians. Certain traditional remedies are also included. The work has no pretensions to style, and contains many colloquialisms. The greater part of it was transferred without acknowledgment to the work of Marcellus Empiricus (c. 410), De Medicamentis Empiricis, Physicis, et Rationabilibus, which is of great value for the correction of the text of Largus.
- De compositione medicamentorum liber. Cratandrus, Basileae 1529 Digital edition by the University and State Library Düsseldorf
- Kai Brodersen: Scribonius Largus, Der gute Arzt / Compositiones. Latin and German. Marix, Wiesbaden 2016. ISBN 978-3-7374-1017-5
- James Grout: Scribonius Largus, part of the Encyclopædia Romana