Seble Wagaw

From Wikipedia, the free encyclopedia

Seble-Hiwot Wagaw is an American organic chemist who is a senior leader at AbbVie pharmaceuticals outside Chicago, IL.[1]

Background and Education[edit]

Wagaw was born in Addis Ababa, Ethiopia and emigrated to the United States in 1974.[2] Her father, Teshome Gebremichael Wagaw, was a faculty member at the University of Michigan for 28 years, and her mother is Tsehai Wolde-Tsadik.[3] She is one of three children, with an older brother and sister.[4] She received her Bachelor's and MS degrees in Chemistry from the University of Michigan in 1994, and a Ph.D. in organic chemistry with Stephen L. Buchwald at the Massachusetts Institute of Technology in 1999.[5] Her research in the Buchwald lab utilized chiral complexes of Palladium to forge new carbon-nitrogen bonds on Aryl rings.[6]


As a Senior Director for process research and R&D at Abbott Laboratories (later AbbVie) for her entire career, Wagaw has published research on enantiomerically enriched lead molecules using Pybox ligands.[7] She has led exploration into new technologies for her process group, including explorations of flow chemistry and commercial-scale electrochemistry.[8]

She is on the advisory board for Asymchem and co-founded the Cross-industry Women's chemical process group.[5]

Awards and recognition[edit]


  1. ^ Myers, Brian (2023-03-06). "Seble H. Wagaw's 2022 NOS Lecture is Available On-Line". ACS Division of Organic Chemistry. Retrieved 2023-08-23.
  2. ^ "Events | U-M LSA Chemistry". Retrieved 2022-01-25.
  3. ^ "Teshome G. Wagaw Obituary (1930 - 2019) Ann Arbor News". Retrieved 2022-01-25.
  4. ^ "Seble-Hiwot Wagaw | Ann Arbor District Library". Retrieved 2020-07-09.
  5. ^ a b "Asymchem Laboratories(Tianjin) Co., Ltd". Retrieved 2020-07-09.
  6. ^ "Events | U-M LSA Chemistry". Retrieved 2020-07-09.
  7. ^ Barnes, David M.; Ji, Jianguo; Fickes, Michael G.; Fitzgerald, Michael A.; King, Steven A.; Morton, Howard E.; Plagge, Frederick A.; Preskill, Margo; Wagaw, Seble H.; Wittenberger, Steven J.; Zhang, Ji (2002-11-01). "Development of a Catalytic Enantioselective Conjugate Addition of 1,3-Dicarbonyl Compounds to Nitroalkenes for the Synthesis of Endothelin-A Antagonist ABT-546. Scope, Mechanism, and Further Application to the Synthesis of the Antidepressant Rolipram". Journal of the American Chemical Society. 124 (44): 13097–13105. doi:10.1021/ja026788y. ISSN 0002-7863. PMID 12405837.
  8. ^ "Amping up the pharma lab: Drug companies explore the potential of electrochemistry". Chemical & Engineering News. Retrieved 2020-07-09.
  9. ^ "1995 Ford Foundation Fellowships". Retrieved 2020-07-09.
  10. ^ Science Spectrum. Career Communications Group. September–October 2004.
  11. ^ "WCC Names Rising Stars | Chemical & Engineering News". Retrieved 2020-07-09.