SESERI was officially opened on 3 June 2003, on the previous site of Sekolah Seri Puteri which moved to a new site in Cyberjaya. 2004 was the first year for the Form 5 students of Seseri to sit for Sijil Pelajaran Malaysia (SPM)
The 46th Sekolah Berasrama Penuh in Malaysia, the school consists of only female students who got straight As in PMR selected throughout the country.
It consists of an administrative block, a science laboratories block, academic blocks, main hall, a cafeteria, and a playground. In the hostel, there are three residential blocks, a mosque, and a dining hall.
In the recent SPM examination (2012), the school gained GPS of 1.75.
Keynotes: SBP = Sekolah Berasrama Penuh • SJK(C) = Sekolah Jenis Kebangsaan Cina • SJK(T) = Sekolah Jenis Kebangsaan Tamil • SK = Sekolah Kebangsaan • SK(P) = Sekolah Kebangsaan Perempuan • SRK = Sekolah Rendah Kebangsaan • SM = Sekolah Menengah • SMK = Sekolah Menengah Kebangsaan • SMK(P) = Sekolah Menengah Kebangsaan Perempuan • SMKA = Sekolah Menengah Kebangsaan Agama • SMS = Sekolah Menengah Sains • SS = Sekolah Sains