Selenophosphate synthetase 1

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SEPHS1
Protein SEPHS1 PDB 3FD5.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases SEPHS1, SELD, SPS, SPS1, Selenophosphate synthetase 1
External IDs MGI: 1923580 HomoloGene: 56558 GeneCards: 22929
RNA expression pattern
PBB GE SEPHS1 208939 at tn.png

PBB GE SEPHS1 208940 at tn.png

PBB GE SEPHS1 208941 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001195602
NM_001195604
NM_012247

NM_175400

RefSeq (protein)

NP_001182531.1
NP_001182533.1
NP_036379.2

NP_780609.4

Location (UCSC) Chr 10: 13.32 – 13.35 Mb Chr 2: 4.88 – 4.91 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Selenide, water dikinase 1 is an enzyme that in humans is encoded by the SEPHS1 gene.[3][4]

This protein encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Low SC; Harney JW; Berry MJ (Oct 1995). "Cloning and functional characterization of human selenophosphate synthetase, an essential component of selenoprotein synthesis". J Biol Chem. 270 (37): 21659–64. doi:10.1074/jbc.270.37.21659. PMID 7665581. 
  4. ^ a b "Entrez Gene: SEPHS1 selenophosphate synthetase 1". 

Further reading[edit]