Selkirk may refer to:
- Selkirk, Scottish Borders, a royal burgh in southern Scotland, incorporated before 1300, and from which many of the following people and places are named
- Fort Selkirk, Yukon, a historic Hudson's Bay Company trading post and First Nation settlement on the Yukon River
- International Selkirk Loop, a route in Idaho, Washington, and British Columbia skirting the Selkirk Mountains
- Lord Selkirk Park, a neighbourhood in Winnipeg, Canada
- Selkirk, Manitoba, a city in Manitoba, Canada
- Selkirk, Kansas, an unincorporated community in Wichita County, Kansas
- Selkirk, Missouri, a ghost town
- Selkirk, New York, an unincorporated hamlet in the town of Bethlehem located in Albany County, New York
- Selkirk Mountains, a mountain range in British Columbia, Canada; the Idaho panhandle, and far eastern Washington State, USA
- Selkirk Settlers Bridge, in Winnipeg, Canada
- Selkirk Shores State Park, on the shore of Lake Ontario, located in the town of Richland, Oswego County, New York
- Alejandro Selkirk Island, the largest and most westerly island in the Juan Fernández Archipelago of the Valparaíso Region of Chile, situated 180 km (100 nmi; 110 mi) west of Robinson Crusoe Island in the southeastern Pacific Ocean.
- Selkirk (surname), surname origin, and list of people with the surname
- Earl of Selkirk, a title in the Peerage of Scotland
- James Douglas-Hamilton, Baron Selkirk of Douglas, Scottish politician and Life Peer, briefly 11th Earl of Selkirk
- Thomas Douglas, 5th Earl of Selkirk, Scottish philanthropist who sponsored immigrant settlements in Canada
- Selkirk (horse), (1988–2013), a North American-bred, thoroughbred racehorse that raced mainly in Europe
- Selkirk Rex, a breed of cat with curly hair
- Selkirk College, a community college in British Columbia
- Selkirk Secondary School, a high school in Kimberley, British Columbia
- Selkirk F.C., a football club
- Selkirk RFC, a rugby club
- Winnipeg Selkirks, a former ice hockey team from Winnipeg, Canada, see List of ice hockey teams in Manitoba
- Selkirk hurdle, a description of the route that freight trains must take from New York City to points west of the Hudson River
- Selkirk locomotive, a type of steam locomotive built by Montreal Locomotive Works
- Selkirk Communications a defunct Canadian radio and television broadcasting company, which operated from 1959 to 1989.
- Selkirk Grace commonly recited before a Burns supper, attributed to Robert Burns
- Selkirk transmitting station, the transmitter that provides FM, digital radio and television coverage to Selkirk.
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