Semenogelase

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Semenogelase
Identifiers
EC number 3.4.21.77
CAS number 95829-41-7&title= 110157-83-0, 95829-41-7
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Semenogelase (EC 3.4.21.77, prostate-specific antigen, alpha-seminoprotein, seminin, P-30 antigen, antigen (human clone HPSA-1 prostate-specific protein moiety reduced), gamma-seminoglycoprotein (human protein moiety reduced), gamma-SM, antigen PSA (human prostate-specific), human glandular kallikrein, antigen PSA (human clone 5P1 protein moiety reduced)) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Preferential cleavage: -Tyr-

This peptidase from trypsin family is present in seminal plasma.

See also[edit]

References[edit]

  1. ^ Digby, M.; Zhang, X.-Y.; Richards, R.I. (1989). "Human prostate specific antigen (PSA) gene: structure and linkage to the kallikrein-like gene, hGK-1". Nucleic Acids Res. 17: 2137–2137. doi:10.1093/nar/17.5.2137. PMC 317563Freely accessible. PMID 2467258. 
  2. ^ Christensson, A.; Laurell, C.-B.; Lilja, H. (1990). "Enzymatic activity of prostate-specific antigen and its reactions with extracellular serine proteinase inhibitors". Eur. J. Biochem. 194: 755–763. doi:10.1111/j.1432-1033.1990.tb19466.x. PMID 1702714. 

External links[edit]