Semenogelin I

SEMG1
Identifiers
Aliases	SEMG1, CT103, SEMG, SGI, dJ172H20.2, Semenogelin I, semenogelin 1
External IDs	OMIM: 182140; HomoloGene: 130511; GeneCards: SEMG1; OMA:SEMG1 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	45,209,768 bp
RNA expression pattern
	Top expressed in
	seminal vesicula; ; sperm; ; prostate; ; gallbladder; ; epithelium of colon; ; thymus; ; synovial joint; ; blood; ; islet of Langerhans; ; mucosa of nose;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; metal ion binding; zinc ion binding;
Cellular component	extracellular region; extracellular exosome; nucleus; extracellular space; protein-containing complex;
Biological process	negative regulation of calcium ion import; insemination; antibacterial humoral response; positive regulation of serine-type endopeptidase activity; protein heterooligomerization; negative regulation of flagellated sperm motility; antimicrobial humoral response; coagulation; sperm capacitation;
	Sources:Amigo / QuickGO
Orthologs
	6406
	n/a
	ENSG00000124233
	n/a
	P04279
	n/a
	NM_198139; NM_003007
	n/a
	NP_002998
	n/a
	Wikidata
View/Edit Human

Semenogelin-1 is a protein that in humans is encoded by the SEMG1 gene.^[3]^[4]^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000124233 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lilja H; Abrahamsson PA; Lundwall A (Mar 1989). "Semenogelin, the predominant protein in human semen. Primary structure and identification of closely related proteins in the male accessory sex glands and on the spermatozoa". J Biol Chem. 264 (3): 1894–900. PMID 2912989.
^ Jonsson M; Linse S; Frohm B; Lundwall A; Malm J (Apr 2005). "Semenogelins I and II bind zinc and regulate the activity of prostate-specific antigen". Biochem J. 387 (Pt 2): 447–53. doi:10.1042/BJ20041424. PMC 1134973. PMID 15563730.
^ "Entrez Gene: SEMG1 semenogelin I".