|Systematic (IUPAC) name|
|Molar mass||345.39 g/mol|
Semorphone is a partial agonist at μ-opioid receptors. It is around twice the potency of morphine, but with a ceiling effect on both analgesia and respiratory depression which means that these effects stop becoming any stronger after a certain maximum dose.
It is not currently used in medicine, and is not a controlled drug, although it might be considered to be a controlled substance analogue of oxymorphone on the grounds of its related chemical structure in some jurisdictions such as the United States, Canada, Australia and New Zealand.
- Behne M, Bremerich D, Heinrich J, Schumacher H, Scherer M. Respiratory effects and tolerability of Mr 2264 Cl. A new opiate partial agonist in comparison with morphine and placebo. European Journal of Clinical Pharmacology. 1994;46(4):301-4.