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A sequestrant is a food additive which improves the quality and stability of foods. A sequestrant forms chelate complexes with polyvalent metal ions, especially copper, iron and nickel, which can prevent the oxidation of the fats in the food. Sequestrants are a type of preservative.

The name comes from Latin and means "to withdraw from use"[citation needed].

Common sequestrants are:

Sodium and calcium salts of EDTA are also commonly used in many foods and beverages.