Sergei Makarov or Sergey Makarov may refer to:
- Sergei Makarov (ice hockey) (born 1958), Russian ice hockey right winger and two-time Olympic gold medalist
- Sergei Makarov (ice hockey, born 1964), Russian ice hockey defenceman
- Sergei Vladimirovich Makarov (born 1987), Russian football defender
- Sergey Makarov (athlete) (born 1973), Russian javelin thrower.
- Sergey Makarov (volleyball) Russian volleyball player
- Sergei Makarov (footballer, born 1996) Russian football midfielder
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