Manukyan started playing jazz when he was 12, and he formed his first jazz band when he was in school. After graduating from Grozny music college he started playing in a Radio and TV jazz orchestra. He received a prize by the Vocalists International Competition in Poland. In 1980's he participated to the major Soviet jazz festivals in Riga, Leningrad and Novosibirsk, played with "Avitsenna" band (Tallinn). Since 1985 he lives in Moscow. Manukyan cooperates with Anatoly Kroll, Richard Elliot, Carlos Santana, George Benson, and Herby Hancock.
- 1989 — grand-prize of all-Soviet TV Music competition, prize of public sympathy
- 1994 — the Best Jazz musician in Russia and "Ovatsia" award
- 1997 — Sekreti
- 1999 — Your Smile