Sermorelin

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Sermorelin
Clinical data
Trade names Geref, Gerel
Synonyms GRF 1–29
AHFS/Drugs.com Micromedex Detailed Consumer Information
Pregnancy
category
  • US: C (Risk not ruled out)
Routes of
administration
Injection
ATC code
Legal status
Legal status
  • US: Discontinued
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
Formula C149H246N44O42S
Molar mass 3357.882 g/mol
3D model (JSmol)
 NYesY (what is this?)  (verify)

Sermorelin (INN) (brand names Geref, Gerel), also known as GHRH (1-29), is a peptide analogue of growth hormone-releasing hormone (GHRH) which is used as a diagnostic agent to assess growth hormone (GH) secretion for the purpose of diagnosing growth hormone deficiency. It is a 29-amino acid polypeptide representing the 1–29 fragment from endogenous human GHRH, thought to be the shortest fully functional fragment of GHRH.[1][2]

See also[edit]

References[edit]

  1. ^ Prakash A, Goa KL (August 1999). "Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency". BioDrugs. 12 (2): 139–57. PMID 18031173. doi:10.2165/00063030-199912020-00007. 
  2. ^ Pharmacology (Rang, Dale, Ritter & Moore, ISBN 0-443-07145-4, 5th ed., Churchill Livingstone 2003).