Serous carcinoma

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Serous carcinoma
Serous carcinoma cytology.jpg
Micrograph of serous carcinoma.
Classification and external resources

In pathology, serous carcinoma is an epithelial malignancy (carcinoma) that arises from the lining of a cavity that produces a serum-like fluid (a serous cavity).

Serous lined cavities include the peritoneum, pericardium and pleural space and tunica vaginalis.[1]

Cytologic features[edit]

Cytologic features of serous carcinoma are:[citation needed]

  • Marked intragroup nuclear pleomorphism.
  • Macronucleoli.
  • "Knobby" group borders (in large groups).
  • Hydropic vacuoles.

Symptoms of serous carcinoma may include:[2]

  • Discomfort/pain or bloating in abdomen
  • Frequent urination
  • Weight loss

Differential diagnosis[edit]

The differential diagnosis of serous carcinoma not otherwise specified includes:

There has been the suggestion that the above diagnoses really represent one entity.[3]

See also[edit]


  1. ^ Serous Membranes & Cavities Lecture. Veterinary Anatomy Web Site. University of Minnesota. URL: Accessed on: February 6, 2010.
  2. ^ "Serous Carcinoma: A Detailed Guide". The CG Law Firm. Retrieved 26 October 2014. 
  3. ^ Dubeau, L. (Dec 2008). "The cell of origin of ovarian epithelial tumours.". Lancet Oncol. 9 (12): 1191–7. doi:10.1016/S1470-2045(08)70308-5. PMID 19038766.