Sertoli cell nodule

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Sertoli cell nodule
Sertoli cell nodule high mag.jpg
Micrograph of a Sertoli cell nodule. H&E stain.
Classification and external resources

A Sertoli cell nodule, also Pick's adenoma, testicular tubular adenoma and tubular adenoma of the testis, is a benign proliferation of Sertoli cells that arises in association with cryptorchidism (undescended testis). They are not composed of a clonal cell population, i.e. neoplastic; thus, technically, they should not be called an adenoma.[1]


Sertoli cell nodules are unencapsulated nodules that consist of:[1][2]

  1. cells arranged in well-formed tubules (that vaguely resemble immature Sertoli cells), with
  2. bland hyperchromatic oval/round nuclei that are stratified, and
  3. may contain eosinophilic (hyaline) blob in lumen (centre).

Additional images[edit]

See also[edit]


  1. ^ a b Tadrous, Paul J. (2007). Diagnostic criteria handbook in histopathology: a surgical pathology vade mecum. John Wiley & Sons Canada Ltd. p. 227. ISBN 978-0-470-51903-5. 
  2. ^ Ricco R, Bufo P (October 1980). "[Histologic study of 3 cases of so-called tubular adenoma of the testis]". Boll. Soc. Ital. Biol. Sper. (in Italian). 56 (20): 2110–5. PMID 6109541. 

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