Shah M. Faruque

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Shah Mohammad Faruque
Shah Faruque-1.jpg
Born 1956 (age 58–59)
Jessore District, East Pakistan (now Bangladesh)
Alma mater University of Dhaka
University of Reading

Shah Mohammad Faruque (born c. 1956) is a Bangladeshi scientist. His research focuses onVibrio cholerae, the bacterium which causes the epidemic diarrhoeal disease Cholera. Currently he is the director of the Centre for Food and Water Borne Diseases at the International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B). His areas of interest include microbial genetics, molecular epidemiology, environmental microbiology, ecology, and evolution of bacterial pathogens, particularly those associated with waterborne and foodborne diseases. Faruque is known for his work on molecular genetics, epidemiology and ecology of the cholera pathogen.[1]

Faruque is a Fellow of TWAS, the World Academy of Sciences, as well as a Fellow of the Bangladesh Academy of Sciences. He is a member of the International Society for Infectious Diseases, ISID, and a founding member of the Association of Vibrio Biologists, AViB.

Early life and education[edit]

Shah Mohammad Faruque was born in Jessore District, Bangladesh in 1956. He received his early education in Jessore Sacred Heart School, Jessore Zilla School, Jhenidah Cadet College, and Jessore Government M.M. College. Faruque received his BSc, and MSc degrees from the department of Biochemistry, Dhaka University in 1978 and 1979 respectively. He obtained his PhD in 1988 from the University of Reading,in the UK. In Reading, he worked on hormonal regulation of gene expression. He was a Commonwealth Scholar in the UK.


Faruque joined the faculty of the Department of Biochemistry at the University of Dhaka and taught biochemistry and molecular biology courses. He later joined ICDDR,B as a scientist, and pioneered molecular biology research in Bangladesh. In ICDDR,B, he set up the Molecular Genetics Laboratory, which is currently highly reputed for conducting and publishing outstanding research work. In recognition of his contributions to the understanding of natural phenomena associated with the dynamics of cholera epidemics, he was awarded the "TWAS Prize-2005" in Medical Sciences, by the TWAS. Faruque collaborates with scientists from different countries and Institutes in India, Japan, Thailand, Sweden, UK, and the US.

Addressing the health problems of developing countries, Faruque has contributed significantly to the understanding of natural mechanisms associated with the emergence of bacterial pathogens. Although he has conducted significant work in understanding the epidemiology and transmission of Shigella and diarrhoeagenic Escherichia coli infections, his major contribution is in the epidemiology and genetics of Vibrio cholerae, the causative agent of cholera epidemics. In collaboration with John Mekalanos, Adele H. Lehman Professor of Microbiology, Harvard Medical School, Boston, Faruque has contributed extensively to the recent understanding of the epidemiology, transmissibility and ecology of Vibrio cholerae. Their work showed the genetic basis for the origin and evolution of new Vibrio cholerae strains with epidemic potential and the role of bacteriophages in this process. They characterised several novel filamentous phages (e.g., KSF-1, RS1 and TLC satellite phages) of Vibrio cholerae, and contributed substantially to understanding the molecular mechanisms for transmission of these phages, and their role in Vibrio cholerae evolution. Faruque has proposed models to explain the role of environmental and host factors and lytic bacteriophages in the ecology of Vibrio cholerae, that supports a self-limiting nature of seasonal cholera epidemics.


Faruque was awarded the TWAS Prize in Medical Sciences in 2005.[2]

Personal life[edit]

Faruque is married to Hasna Hena. They have two children - Elora Faruque and Shah Nayeem Faruque.


As of 2012, Faruque has authored more than 120 original research papers, reviews, and book chapters. His work have been published in top ranking international scientific journals, including Nature,[3] PNAS, Lancet and ASM Journals. He has also edited a number of books which include Vibrio cholerae: Genomics and Molecular Biology (2008), and Foodborne and Waterborne Bacterial Pathogens (2012).[4]


  1. ^ Thomas Häusler Viruses Vs. Superbugs: A Solution to the Antibiotics Crisis? 2007 Page 89
  2. ^ "Dr Shah M Faruque rewarded" (PDF). Glimpse (ICDDR,B) 28 (2–3): 7. June–September 2006. 
  3. ^ Hassan, Faizule; Kamruzzaman, M.; Mekalanos, John J.; Faruque, Shah M. (21 October 2010). "Satellite phage TLCφ enables toxigenic conversion by CTX phage through dif site alteration". Nature 467 (7318): 982–985. doi:10.1038/nature09469. 
  4. ^ ICDDRB Support for Faruque CV, publications and bio

External links[edit]

  1. Shah M. Faruque on
  2. interview on cholera in Bengali on