Sick cell syndrome

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Not to be confused with Sickle-cell disease.

Sick cell syndrome or cell sickness syndrome is a medical condition characterised by reduced functioning of the cellular Na+/K+ pump,[1] which is responsible for maintaining the internal ion homeostasis. The clinical result is a rise in blood K+ level and drop of blood Na+ levels

There are a wide range of possible pathological conditions that can cause sick cell syndrome, including:

This syndrome is well known in the field of palliative medicine as many terminal patients develop this condition.


  1. ^ Benito Ruiz, J; Baena Montilla, P; Navarro Monzonis, A (Aug 1990). "Sick cell syndrome in a burned patient". Burns. 16 (4): 309–12. doi:10.1016/0305-4179(90)90147-O. ISSN 0305-4179. PMID 2257076.