Silas Weir Mitchell (physician)

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Silas Weir Mitchell
Born(1829-02-15)February 15, 1829
DiedJanuary 4, 1914(1914-01-04) (aged 84)
Philadelphia, Pennsylvania, US
Alma materJefferson Medical College
Known forneurology research
SpouseMary Cadwalader
RelativesSilas Weir Mitchell (descendant)

Silas Weir Mitchell (February 15, 1829 – January 4, 1914) was an American physician, scientist, novelist, and poet. He is considered the father of medical neurology, and he discovered causalgia (complex regional pain syndrome) and erythromelalgia, and pioneered the rest cure.

Early life[edit]

Silas Weir Mitchell was born on February 15, 1829, in Philadelphia, Pennsylvania, to prominent physician and writer John Kearsley Mitchell (1792–1858) and Sarah Henry Mitchell (1800–1872) .

He studied at Philadelphia's renowned University of Pennsylvania and later earned the degree of MD at the city's Jefferson Medical College in 1850.


During the Civil War, he was director of treatment of nervous injuries and maladies at Turner's Lane Hospital, Philadelphia, and at the close of the war became a specialist in neurology. In this field Mitchell pioneered the rest cure for diseases now termed "psychiatric", particularly neurasthenia and hysteria, subsequently taken up by the medical world.[1] The treatment consisted primarily in isolation, confinement to bed, dieting, electrotherapy and massage; and was popularly known as 'Dr Diet and Dr Quiet'.[1] Mitchell advocated a high-fat diet to his patients.[2][3] He believed that a diet rich in fat would "fatten and redden" his patients, leading to a cure. To achieve this, large quantities of milk were prescribed. He requested his patients to consume two quarts or more milk a day.[4]

His medical texts include Injuries of Nerves and Their Consequences (1872) and Fat and Blood (1877). Mitchell's disease (erythromelalgia) is named after him. He also coined the term phantom limb during his study of an amputee.[5] Mitchell discovered and treated causalgia (today known as CRPS/RSD), a condition most often encountered by hand surgeons. Mitchell is considered the father of medical neurology and a pioneer of "evidence-based" or "scientific" medicine. He was a founding member of the American Anthropometric Society whose purpose was to collect the brains of eminent scientists to further brain science.[6] He was also a psychiatrist, toxicologist, author, poet, and celebrity in Europe as well as America. His contemporaries considered him a genius no less than Benjamin Franklin.

In 1866, he published a short story in the Atlantic Monthly resting upon both somatic and psychological insights entitled "The Case of George Dedlow".[7] From that point onward, Mitchell divided his attention between scientific and literary pursuits. In the former field, he produced monographs on rattlesnake venom, intellectual hygiene, injuries to the nerves, neurasthenia, nervous diseases of women, the effects of gunshot wounds upon the nervous system, and relations between nurse, physician, and patient; in the latter, he wrote juvenile stories, several volumes of respectable verse (The Hill of Stones and Other Poems was published in 1883 by Houghton, Mifflin and Co.), and prose fiction of varying merit, which earned him a leading place among American authors at the close of the 19th century. His historical novels in particular, notably Hugh Wynne (1897), The Adventures of François (1898), The Youth of Washington (1904), and The Red City (1909), are among the best of their genre.

Prominent patients[edit]

Although Silas Weir Mitchell was considered the most prominent doctor of the time, his female patients often suffered under his care. There was even a death due to his treatment that was not revealed to the public.

He was Charlotte Perkins Gilman's doctor and his use of a rest cure on her provided the idea for "The Yellow Wallpaper", a short story in which the narrator is driven insane by this treatment.

His treatment was also used on Virginia Woolf, who wrote a savage satire of it in her novel Mrs. Dalloway (1925): "you invoke proportion; order rest in bed; rest in solitude; silence and rest; rest without friends, without books, without messages; six months rest; until a man who went in weighing seven stone six comes out weighing twelve".[8]

Influence on Freud[edit]

Sigmund Freud reviewed Mitchell's book on The Treatment of Certain Forms of Neurasthenia and Hysteria in 1887;[9] and used electrotherapy in his work into the 1890s.[10]

Freud also adopted Mitchell's use of physical relaxation as an adjunct to therapy, which arguably led to the institutionalization of the psychoanalytic couch.[11]

Honors and recognition[edit]

Mitchell's eminence in science and letters was recognized by honorary degrees conferred upon him by several universities at home and abroad and by membership, honorary or active, in many American and foreign learned societies. In 1887 he was president of the Association of American Physicians and in 1908–09 president of the American Neurological Association.

He was a trustee of the Carnegie Institution from 1902 until he died in 1914.[12] In 1912 he was honored by the Guggenheim Honor Cup of the Penn Club of New York.[13]

The American Academy of Neurology award for young researchers, the S. Weir Mitchell Award, is named for him.[14]

Crotalus mitchellii, the speckled rattlesnake, was named after Mitchell.[15]

Personal life[edit]

Mitchell was twice married. His first marriage was to Mary Middleton Elwyn (1838–1862), a daughter of Dr. Alfred L. Elwyn of Philadelphia.[16] Before her death, they were the parents of two children:

  • John Kearsley Mitchell (1859–1917),[17] a neurologist who married Anne Keppele Williams in 1890.[16]
  • Langdon Elwyn Mitchell (1862–1935),[18] a playwright who married actress Marion Lea in 1891.[19]

On June 23, 1875, Mitchell was married to Mary Cadwalader (1835–1914),[20] who was from one of Philadelphia's most prestigious families. She was a daughter of Thomas McCall Cadwalader and Maria Charlotte Gouverneur (niece of Elizabeth Kortright, who had married U.S. President James Monroe). The marriage "propelled him to one of the city's highest social circles and he became a trustee of the University of Pennsylvania the following year."[21] Together, they were the parents of a daughter:

  • Marie Gouverneur Cadwalader Mitchell (1876–1898), who died unmarried.[22]

Mitchell died on January 4, 1914, in Philadelphia and is interred at The Woodlands Cemetery.[23] His widow died a week after his funeral.[20]

Cultural Club Founder[edit]

Mitchell and 8 other members of the University Club at Penn founded The Franklin Inn Club in 1902.

Art patron[edit]

He was a friend and patron of the artist Thomas Eakins, and owned the painting Whistling for Plover.[24] The Philadelphia Chippendale chairs seen in several Eakins paintings – such as William Rush Carving his Allegorical Figure of Schuylkill River (1877) and the bas-relief Knitting (1883) – were borrowed from Mitchell. Following Eakins's 1886 forced resignation from the Pennsylvania Academy of the Fine Arts, Mitchell may have recommended the artist's trip to the Badlands of South Dakota.

The artist John Singer Sargent painted two portraits of Mitchell: one is in the collection of the College of Physicians of Philadelphia; the other, commissioned by the Mutual Assurance Company of Philadelphia in 1902, was recently sold (see External Links, below).

The sculptor Augustus Saint-Gaudens modeled an 1884 bronze portrait plaque of Mitchell.[25] Mitchell commissioned Saint-Gaudens to create a monument to his deceased daughter Maria: The Angel of Purity, a white marble version of the sculptor's Amor Caritas. Originally installed in Saint Stephen's Church, Philadelphia, it is now at the Philadelphia Museum of Art.

Ghost story[edit]

Some time during the late 1800s, a ghost story was published about Dr. Mitchell that he was never able to lay to rest. The story tells how a very young girl in rags and threadbare shawl came to his door in bad weather and begged him to come take care of her sick mother. The girl guided Mitchell to the sick woman, who turned out to be a former house servant of his who was suffering from pneumonia. Mitchell helped the woman, then congratulated her on having such a fine daughter, but the woman told him her daughter died a month earlier. In a cupboard, Mitchell found the shawl the girl had been wearing; it had not been worn out that night.

A 2011 study determined that the ghost story was likely originally told by Mitchell himself as entertainment at a medical meeting, then took on a life of its own. In his 1910 book "Characteristics," Mitchell wrote about a man who told a story "about a little dead child who rang up a doctor one night, and took him to see her dying mother;" the man was then constantly bothered by believers and disbelievers, and unable to stop the story. In context, it seems that Mitchell was referring to himself.[26]

"The Yellow Wallpaper"[edit]

Charlotte Perkins Gilman would claim her short story "The Yellow Wallpaper" was directed at Mitchell that he might reconsider the rest cure.[27] Although she has claimed to have sent a copy of the story, Mitchell never acknowledged his connection to the infamous story or that he ever received a copy. Perkins Gilman also claimed that Mitchell altered his Rest Cure treatment after reading "The Yellow Wallpaper," but there is no evidence that Mitchell ever changed or altered the Rest Cure.


  • Weir Mitchell skin – a red, glossy, perspiring skin seen in cases of incomplete irritative lesion of a nerve
  • Weir Mitchell treatment – a method of treating neurasthenia, hysteria, etc., by absolute bed rest (aka a rest cure), frequent and abundant feeding, and the systematic use of massage and electricity
  • Mitchell's diseaseerythromelalgia
Dorland's Medical Dictionary (1938)

Selected publications[edit]


  1. ^ a b Ellenberger, Henri F. (August 2008). The Discovery of the Unconscious: The History and Evolution of Dynamic Psychiatry. Basic Books. p. 244. ISBN 978-0-7867-2480-2.
  2. ^ Morris, David B. (1991). The Culture of Pain. University of California Press. p. 113. ISBN 978-0-520-08276-2
  3. ^ Foxcroft, Louise. (2012). Calories & Corsets: A History of Dieting Over 2, 000 Years. Profile Books. p. 99. ISBN 978-1-84668-425-8
  4. ^ Adams, Henry. (2005). Eakins Revealed: The Secret Life of an American Artist. Oxford University Press. p. 460. ISBN 978-0195156683
  5. ^ Woodhouse, Annie (2005). "Phantom limb sensation". Clinical and Experimental Pharmacology and Physiology. 32 (1–2): 132–134. doi:10.1111/j.1440-1681.2005.04142.x. ISSN 0305-1870. PMID 15730449. S2CID 35696871.
  6. ^ Herr, Mickey. "On The Hunt For Brains, Discovering The Wistar Institute". Hidden City Philadelphia. Retrieved December 31, 2023.
  7. ^ Mitchell, Silas Weir (July 1866). "The Case of George Dedlow". Atlantic Monthly. Retrieved January 21, 2014.
  8. ^ Lee, Hermione (1996). Virginia Woolf. London: Chatto & Windus. p. 194. ISBN 9780701165079.
  9. ^ Jones, Ernest (1964). The Life and Work of Sigmund Freud. p. 210.
  10. ^ Gay, Peter (2006). Freud: A Life for Our Time. W. W. Norton. p. 62. ISBN 978-0-393-32861-5.
  11. ^ Ellenberger, p. 518.
  12. ^ Carnegie Institution of Washington. Year Book No. 47, July 1, 1947 – June 30, 1948 (PDF). Washington, DC. 1948. p. vi.{{cite book}}: CS1 maint: location missing publisher (link)
  13. ^ "Guggenheim Honor Cup". Penn History, University of Pennsylvania.
  14. ^ American Academy of Neurology: S. Weir Mitchell award
  15. ^ Beolens, Bo; Watkins, Michael; Grayson, Michael (2011). The Eponym Dictionary of Reptiles. Baltimore: Johns Hopkins University Press. p. 180. ISBN 978-1-4214-0135-5.
  16. ^ a b Andrews, Charles McLean (1907). The Ancestors and Descendants of Ezekiel Williams of Wethersfield 1608-1907. Case, Lockwood & Brainard Company Print] priv. print. p. 48. Retrieved June 15, 2023.
  17. ^ "Dr. John K. Mitchell". The New York Times. April 11, 1917. Retrieved June 15, 2023.
  18. ^ ORK 'l'zams, Special to Tx Nw (October 22, 1935). "L. E. MITCHELL, 75, PLAYWRIGHT, DIES; He Dramatized 'Vanity Fair' Under the Name of 'Becky Sharp' for Mrs, Fiske". The New York Times. Retrieved June 15, 2023.
  19. ^ "MRS. L. E. MITCHELL, FORMER ACTRESS, 83; Widow of Playwright, Poet Is Dead--Played With Langtry". The New York Times. June 9, 1944. Retrieved June 15, 2023.
  20. ^ a b Times, Special to The New York (January 16, 1914). "Mrs. S. Weir Mitchell". The New York Times. Retrieved June 15, 2023.
  21. ^ "Silas Weir Mitchell (1829-1914) | Department of Neurology | Perelman School of Medicine at the University of Pennsylvania". University of Pennsylvania. Retrieved June 15, 2023.
  22. ^ Cervetti, Nancy (August 21, 2015). S. Weir Mitchell, 1829–1914: Philadelphia's Literary Physician. Penn State Press. p. 101. ISBN 978-0-271-07387-3. Retrieved June 15, 2023.
  23. ^ "DR. S. WEIR MITCHELL DEAD.; Neurologist and Author Had Been III With La Grippe". The New York Times. January 4, 1914. Retrieved June 15, 2023.
  24. ^ Reason, Akela (2010). Thomas Eakins and the Uses of History. University of Pennsylvania Press. p. 200. ISBN 978-0-8122-4198-3.
  25. ^ Silas Weir Mitchell by Saint-Gaudens from Smithsonian Institution.
  26. ^ Dr. S. Weir Mitchell's Strange Encounter by Garth Haslam, from the Anomalies website.
  27. ^ Wayne, Teddy; Vincent, Caitlin (eds.). "The Yellow Wallpaper Study Guide". Grade Saver. Retrieved November 16, 2015.


 This article incorporates text from a publication now in the public domainChisholm, Hugh, ed. (1911). "Mitchell, Silas Weir". Encyclopædia Britannica. Vol. 18 (11th ed.). Cambridge University Press. p. 618.

Further reading[edit]

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