Simple columnar epithelium
This article does not cite any sources. (September 2018) (Learn how and when to remove this template message)
|Simple columnar epithelium|
|Latin||simple columnar epithelium|
|This article is part of a series on|
|Squamous epithelial cell|
|Columnar epithelial cell|
|Cuboidal epithelial cell|
A simple columnar epithelium is a single layer of columnar cells attached to the basement membrane, with oval-shaped nuclei located in the basal region. In humans, a simple columnar epithelium lines most organs of the digestive tract including the stomach, small intestine, and large intestine. Simple columnar epithelia line the uterus.
Simple columnar epithelium is further divided into two categories: ciliated and non-ciliated (glandular). The ciliated part of the simple columnar epithelium has tiny hairs which help move mucus and other substances up the respiratory tract.
Non-ciliated types are found in the digestive tract. Ciliated types are found within bronchioles of the respiratory tract and in the oviduct of the female reproductive tract. The non-ciliated columnar epithelium is also found in the inner lining of small intestines.
Ciliated columnar epithelium moves mucus and other substances via cilia and is found in the upper respiratory tract, the fallopian tubes, the uterus, and the central part of the spinal cord. They are the primary target of infection for "common cold viruses" such as coronaviruses, influenza virus and rhinoviruses. These viruses may kill the ciliated cells or stop the cilia beating. In either case, mucus builds up and forms a good site for secondary bacterial infections, resulting in mucus.
Transverse section of a villus, from the human intestine. X 350.
a. Basement membrane, here somewhat shrunken away from the epithelium.
c. Columnar epithelium.
d. Its striated border.
e. Goblet cells.
f. Leucocytes in epithelium.
f’. Leucocytes below epithelium.
g. Blood vessels.
h. Muscle cells cut across.