Togavirin

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Togavirin
Identifiers
EC number3.4.21.90
CAS number342882-56-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Togavirin (EC 3.4.21.90, Sindbis virus protease, Sindbis virus core protein, NsP2 proteinase) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction

Autocatalytic release of the core protein from the N-terminus of the togavirus structural polyprotein by hydrolysis of a -Trp-Ser- bond

This enzyme is isolated from the Sindbis and Semliki forest togaviruses.

References[edit]

  1. ^ Kräusslich HG, Wimmer E (1988). "Viral proteinases". Annual Review of Biochemistry. 57: 701–54. doi:10.1146/annurev.bi.57.070188.003413. PMID 3052288.
  2. ^ Strauss EG, De Groot RJ, Levinson R, Strauss JH (December 1992). "Identification of the active site residues in the nsP2 proteinase of Sindbis virus". Virology. 191 (2): 932–40. doi:10.1016/0042-6822(92)90268-t. PMID 1448929.
  3. ^ Tong L, Wengler G, Rossmann MG (March 1993). "Refined structure of Sindbis virus core protein and comparison with other chymotrypsin-like serine proteinase structures". Journal of Molecular Biology. 230 (1): 228–47. doi:10.1006/jmbi.1993.1139. PMID 8450538.

External links[edit]