Cathedral of Exaltation of the Holy Cross (Croatian: Katedrala Uzvišenja svetog Križa) is a cathedral in the Diocese of Sisak. It is located in the center of Sisak on Ban Jelačić Square.
The church was built in the 18th century and dedicated in 1765. The spire was built in 1760.
After an earthquake in 1909, the old Baroque facade was replaced with a Neoclassical facade, with details in the Art Nouveau style. The church was also damaged during the Croatian War of Independence.
On 5 December 2009 Pope Benedict XVI established the Diocese of Sisak. As a result, the parish church became a cathedral.