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Sluis-Aardenburg was a municipality in the province of Zeeland, in the south-western part of the Netherlands. It was created from a merger of Sluis and Aardenburg in 1995, and it merged with the municipality of Oostburg, on 1 January 2003, to form the new municipality of Sluis. Sluis-Aardenburg covered an area of 83.48 km², of which 0.89 km² was water.
The municipality comprised the following towns, villages and townships:
- Sint Anna ter Muiden
- Sint Kruis