Small nucleolar RNA Me28S-Gm3255

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Small nucleolar RNA Me28S-Gm3255
RF00527.jpg
Predicted secondary structure and sequence conservation of snoMe28S-G3255
Identifiers
Symbol snoMe28S-G3255
Alt. Symbols snoMe28S-G3255a
Rfam RF00527
Other data
RNA type Gene; snRNA; snoRNA; CD-box
Domain(s) Eukaryota
GO 0006396 0005730
SO 0001263
PDB structures PDBe

Small nucleolar RNA Me28S-Gm3255 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA Me28S-Gm3255 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.[1] It is predicted that this family directs 2'-O-methylation of 28S G-3255.[2]

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