Small nucleolar RNA SNORA79
|Small nucleolar RNA SNORA79|
|RNA type||Gene; snRNA; snoRNA; H/ACA-box|
Small nucleolar RNA SNORA79 (also known as ACA65) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA).
SNORA79 was identified by computational screening and its expression in mouse experimentally verified by Northern blot and primer extension analysis. It belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure and the conserved H/ACA-box motifs.
- Schattner, P.; Barberan-Soler, S.; Lowe, T. M. (January 2006). "A computational screen for mammalian pseudouridylation guide H/ACA RNAs". RNA. 12 (1): 15–25. doi:10.1261/rna.2210406. PMC . PMID 16373490.
- Kiss, Arnold M.; Jády, Beáta E.; Bertrand, Edouard; Kiss, Tamás (2004). "Human Box H/ACA Pseudouridylation Guide RNA Machinery". Molecular and Cellular Biology. 24 (13): 5797–5807. doi:10.1128/MCB.24.13.5797-5807.2004. PMC . PMID 15199136.
- Lestrade, Laurent; Weber, Michel J. (2006). "snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs". Nucleic Acids Research. 34 (Supplement 1: Database Issue): D158–D162. CiteSeerX . doi:10.1093/nar/gkj002. PMC . PMID 16381836.
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