Small nucleolar RNA SNORD14
|Small nucleolar RNA SNORD14|
|RNA type||Gene; snRNA; snoRNA; CD-box|
U14 small nucleolar RNA (U14 snoRNA) is a non-coding RNA required for early cleavages of eukaryotic precursor rRNAs. In yeasts, this molecule possess a stem-loop region (known as the Y-domain) which is essential for function. A similar structure, but with a different consensus sequence, is found in plants, but is absent in vertebrates. In human there are two closely related copies called SNORD14A and SNORD14B that are expressed from the intron of their host gene ribosomal protein Rps13.
- Samarsky, DA; Schneider GS; Fournier MJ (1996). "An essential domain in Saccharomyces cerevisiae U14 snoRNA is absent in vertebrates, but conserved in other yeasts". Nucleic Acids Res. 24 (11): 2059–2066. PMC . PMID 8668536. doi:10.1093/nar/24.11.2059.
- Page for Small nucleolar RNA SNORD14 at Rfam
- Entry for U14A at snoRNABase
- Entry for SNORD14A in HGNC database
- Entry for U14B at snoRNABase
- Entry for SNORD14B in HGNC database
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