Small nucleolar RNA SNORD27

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Small nucleolar RNA SNORD27
RF00086.jpg
Identifiers
Symbol SNORD27
Alt. Symbols U27
Rfam RF00086
Other data
RNA type Gene; snRNA; snoRNA; CD-box
Domain(s) Eukaryota
GO 0006396 0005730
SO 0000593
PDB structures PDBe

Small nucleolar RNA SNORD27 (also known as U27 in mammals and snR74 in fungi) is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. U27 is encoded within the U22 snoRNA host gene (UHG) in mammals[1] and is thought to act as a 2'-O-ribose methylation guide for ribosomal RNA.[2] This family also contains several related snoRNAs from yeast and plants.

References[edit]

  1. ^ Tycowski, KT; Shu MD; Steitz JA (1996). "A mammalian gene with introns instead of exons generating stable RNA products". Nature. 379 (6564): 464–466. doi:10.1038/379464a0. PMID 8559254. 
  2. ^ Tycowski, KT; Smith CM; Shu MD; Steitz JA (1996). "A small nucleolar RNA requirement for site-specific ribose methylation of rRNA in Xenopus". Proc Natl Acad Sci USA. 93 (25): 14480–14485. doi:10.1073/pnas.93.25.14480. PMC 26158Freely accessible. PMID 8962077. 

External links[edit]