|Group:||Group IV ((+)ssRNA)|
Sobemovirus is a genus of viruses. Plants serve as natural hosts. There are currently 14 species in this genus including the type species Southern bean mosaic virus. Diseases associated with this genus include: mosaics and mottles.
Viruses in Sobemovirus are non-enveloped, with icosahedral geometries, and T=3 symmetry. The diameter is around 30 nm. Genomes are circular and non-segmented, around 4kb in length.
|Genus||Structure||Symmetry||Capsid||Genomic Arrangement||Genomic Segmentation|
Viral replication is cytoplasmic. Entry into the host cell is achieved by penetration into the host cell. Replication follows the positive stranded RNA virus replication model. Positive stranded RNA virus transcription is the method of transcription. Translation takes place by leaky scanning, and -1 ribosomal frameshifting. The virus exits the host cell by tubule-guided viral movement. Plants serve as the natural host. The virus is transmitted via a vector (CFMV: insects). Transmission routes are vector and seed borne.
|Genus||Host Details||Tissue Tropism||Entry Details||Release Details||Replication Site||Assembly Site||Transmission|
|Sobemovirus||Plants||None||Penetration||Viral Movement||Cytoplasm||Cytoplasm||Vector, Seed borne|
ORF1 encodes P1 which plays a role in suppression of silencing and virus movement.
ORFs 2a and 2b encode the replicational polyproteins P2a and P2ab. Translation of ORF2a from the genomic RNA is dependent on a leaky scanning mechanism.
ORF3 encodes the coat protein.
ORFx is conserved in all sobemoviruses. It overlaps the 5' end of ORF2a in the +2 reading frame and also extends some distance upstream of ORF2a. It lacks an AUG initiation codon and its expression is predicted to depend on low level initiation at near-cognate non-AUG codons, such as CUG, by a proportion of the ribosomes that are scanning the region between the ORF1 and ORF2a initiation codons. Its function is unknown but it appears to be essential for infection.
- "Viral Zone". ExPASy. Retrieved 15 June 2015.
- ICTV. "Virus Taxonomy: 2014 Release". Retrieved 15 June 2015.
- Index of Viruses—Sobemovirus (2006). In: ICTVdB—The Universal Virus Database, version 4. Büchen-Osmond, C (Ed), Columbia University, New York, USA.
- Ling R, Pate AE, Carr JP, Firth AE. An essential fifth coding ORF in the sobemoviruses. Virology pii: S0042-6822(13)00314-0. doi: 10.1016/j.virol.2013.05.033