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Medication group
A sodium channel opener is a type of drug which facilitates ion transmission through sodium channels .
Examples include toxins , such as aconitine , veratridine , batrachotoxin , robustoxin , palytoxin and ciguatoxins and insecticides (DDT and pyrethroids ), which activate voltage-gated sodium channels (VGSCs), and solnatide (AP301), which activates the epithelial sodium channel (ENaC).[ 1]
^ Shabbir W, Tzotzos S, Bedak M, Aufy M, Willam A, Kraihammer M, Holzner A, Czikora I, Scherbaum-Hazemi P, Fischer H, Pietschmann H, Fischer B, Lucas R, Lemmens-Gruber R (2015). "Glycosylation-dependent activation of epithelial sodium channel by solnatide". Biochem. Pharmacol . 98 (4): 740–53. doi :10.1016/j.bcp.2015.08.003 . PMID 26254591 .
Calcium
VDCCs Tooltip Voltage-dependent calcium channels
Potassium
VGKCs Tooltip Voltage-gated potassium channels
IRKs Tooltip Inwardly rectifying potassium channel
KCa Tooltip Calcium-activated potassium channel
K2Ps Tooltip Tandem pore domain potassium channel
Sodium
VGSCs Tooltip Voltage-gated sodium channels
ENaC Tooltip Epithelial sodium channel
ASICs Tooltip Acid-sensing ion channel
Chloride
CaCCs Tooltip Calcium-activated chloride channel
CFTR Tooltip Cystic fibrosis transmembrane conductance regulator
Unsorted
Others
TRPs Tooltip Transient receptor potential channels LGICs Tooltip Ligand gated ion channels
