Sodium orthovanadate

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Sodium orthovanadate
Na3VO4dihydrate.tif
Names
IUPAC name
Sodium vanadate(V)
Other names
Sodium vanadium oxide
Identifiers
3D model (JSmol)
ChEMBL
ECHA InfoCard 100.033.883
RTECS number YW1120000
Properties
Na3VO4
Molar mass 183.908 g/mol
Appearance white powder
Density 2.16 g/cm3, solid
Melting point 858 °C (1,576 °F; 1,131 K)
22.17 g/100 mL
Solubility insoluble in ethanol
Structure
cubic
Thermochemistry
164.8 J/mol K
190 J/mol K
−1757 kJ/mol
Hazards
Main hazards Harmful.
NFPA 704
Flammability code 0: Will not burn. E.g., waterHealth code 3: Short exposure could cause serious temporary or residual injury. E.g., chlorine gasReactivity code 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g., liquid nitrogenSpecial hazards (white): no codeNFPA 704 four-colored diamond
0
3
0
Flash point Non-flammable
Lethal dose or concentration (LD, LC):
330 mg/kg (oral, rat)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
No verify (what is YesYNo ?)
Infobox references

Sodium orthovanadate is the inorganic compound with the chemical formula Na3VO4·2H2O (sodium orthovanadate dihydrate). It is a salt of the VO3−
4
oxyanion. It is a colorless, water-soluble solid.[2]

Synthesis and structure[edit]

Sodium orthovanadate is produced by dissolving vanadium(V) oxide in a solution of sodium hydroxide:

V2O5 + 6 NaOH → 2 Na3VO4 + 3 H2O

The salt features tetrahedral VO3−
4
centers linked to octahedral Na+ sites.[3]

Reactions[edit]

Acidification of orthovanadate induces condensation to polyoxovanadates, specifically decavanadate.[4]

Vanadates exhibit a variety of biological activities, in part because they serve as structural mimics of phosphates.[5][6] For this reason, vanadates are commonly used as tyrosine phosphatase inhibitors.

References[edit]

  1. ^ http://www.sciencelab.com/msds.php?msdsId=9925008
  2. ^ Greenwood, Norman N.; Earnshaw, Alan (1997). Chemistry of the Elements (2nd ed.). Butterworth-Heinemann. ISBN 0-08-037941-9. 
  3. ^ Kato, K.; Takayama-Muromachi, E. (1987). "Die Struktur des Trinatriumvanadattrihydrats" [The structure of trisodium vanadate trihydrate]. Acta Crystallogr. C43: 1030–1032. doi:10.1107/S0108270187093120. 
  4. ^ Klemperer, W. G.; Yaghi, O. (1983). "Tetrabutylammonium Trihydrogen Decavanadate(V)". Inorg. Synth. 27: 83. doi:10.1002/9780470132586.ch15. 
  5. ^ Korbecki, Jan; Baranowska-Bosiacka, Irena; Gutowska, Izabela; Chlubek, Dariusz (2012). "Biochemical and medical importance of vanadium compounds" (PDF). Acta Biochim. Polon. 59: 195–200. 
  6. ^ Crans, D. C.; Chatterjee, P. B. (2013). "Vanadium biochemistry". In Reedijk, Jan; Poeppelmeier, Kenneth. Comprehensive Inorganic Chemistry II. 3. pp. 323–342. doi:10.1016/B978-0-08-097774-4.00324-7. ISBN 978-0-08-097774-4. 

See also[edit]