Solasodine

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Solasodine
Solasodine.svg
Names
IUPAC name
(3β,22α,25R)-Spirosol-5-en-3-ol
Other names
Purapuridine; Solancarpidine; Solanearpidine; Solanidine-S
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.004.341
EC Number 204-774-2
KEGG
Properties
C27H43NO2
Molar mass 413.65 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Solasodine is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family.[1] Solasonine and solamargine are glycoalkaloid derivatives of solasodine.[1] Solasodine is teratogenic to hamster fetuses in a dose of 1200 to 1600 mg/kg.[2] Literature survey reveals that solasodine has diuretic, anticancer, antifungal, cardiotonic, antispermatogenetic, antiandrogenic, immunomodulatory, antipyretic and various effects on central nervous system. [3]

Uses[edit]

It is commercially used as a precursor for the production of complex steroidal compounds such as contraceptive pills.[1]

See also[edit]

References[edit]

  1. ^ a b c Everist, S.L. (1981). Poisonous Plants of Australia. Angus & Robertson. ISBN 0-207-14228-9. 
  2. ^ Kinghorn, A.D. (2010). "Toxins and Teratogens of the Solanaceae and Liliaceae". Toxic plants. Society for Economic Botany, Columbia University Press. pp. 75–76. ISBN 0231515685. 
  3. ^ Patel, Kanika; Singh, Ravi B.; Patel, Dinesh K. (2013). "Medicinal significance, pharmacological activities, and analytical aspects of solasodine: A concise report of current scientific literature". Journal of Acute Disease. 2 (2): 92–98. doi:10.1016/S2221-6189(13)60106-7.