Somatostatin receptor 4

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Somatostatin receptor 4
Symbols SSTR4 ; SS-4-R; SS4-R; SS4R
External IDs OMIM182454 MGI105372 HomoloGene20286 IUPHAR: 358 ChEMBL: 1853 GeneCards: SSTR4 Gene
RNA expression pattern
PBB GE SSTR4 214556 at tn.png
More reference expression data
Species Human Mouse
Entrez 6754 20608
Ensembl ENSG00000132671 ENSMUSG00000037014
UniProt P31391 P49660
RefSeq (mRNA) NM_001052 NM_009219
RefSeq (protein) NP_001043 NP_033245
Location (UCSC) Chr 20:
23.04 – 23.04 Mb
Chr 2:
148.4 – 148.4 Mb
PubMed search [1] [2]

Somatostatin receptor type 4 is a protein that in humans is encoded by the SSTR4 gene.[1][2]

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR4 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in fetal and adult brain and lung.[2]

See also[edit]


  1. ^ Rohrer L, Raulf F, Bruns C, Buettner R, Hofstaedter F, Schule R (Jun 1993). "Cloning and characterization of a fourth human somatostatin receptor". Proc Natl Acad Sci U S A 90 (9): 4196–200. doi:10.1073/pnas.90.9.4196. PMC 46473. PMID 8483934. 
  2. ^ a b "Entrez Gene: SSTR4 somatostatin receptor 4". 

Further reading[edit]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.