"Song to Say Goodbye" is the second single from Placebo's fifth studio album, Meds. It was produced by Dimitri Tikovoi. The first single, "Because I Want You" was only released in the United Kingdom, so elsewhere, "Song to Say Goodbye" is considered the first single from Meds. The song develops around piano notes that repeat throughout it. The song deals with heroinaddiction and its influence on the relationships of the parties involved.
There is a live version available of the song on the live EP Live at La Cigale.
The cover art features a blurred picture of vocalist Brian Molko.
The original video written and directed by Philippe André portrays a mentally challenged father (played by Michael Carr) while his son (played by Field Cate) is trying to cope with his dad's condition. It could also be interpreted as a role-reversal between father and son. Philippe André made a 10 minutes extended version of the music video. Placebo remixed the track for the film released on DVD by Virgin.