Sophora flavescens

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Sophora flavescens
Sophora flavescens.jpg
Scientific classification
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S. flavescens
Binomial name
Sophora flavescens

Sophora flavescens, the shrubby sophora,[1] is a species of plant in the genus Sophora of the family Fabaceae. This genus contains about 52 species, nineteen varieties, and seven forms that are widely distributed in Asia, Oceania, and the Pacific islands. About fifteen of these species have a long history of use in traditional Chinese medicines.[2]

Growth and cultivation[edit]

Sophora flavescens is an evergreen slow growing shrub growing to 1.5 m (4.9 ft) by 1 m (3.3 ft). It is hardy to 0–10 °F (−18 – −12 °C) and to US zone 6. The plant prefers light (sandy), medium (loamy) and heavy (clay) soils and requires well-drained soil. The plant prefers acid, neutral and basic (alkaline) soils. It cannot grow in the shade. It requires moist soil. Like many other species in the family Fabaceae, this species can fix nitrogen.[citation needed]

Chemistry[edit]

Matrine (left) and its oxide

Chemical compounds isolated from S. flavescens include:

Toxicity[edit]

Toxic effects from use of the root may include nausea, dizziness, vomiting, constipation, spasms, disturbance of speech, irregular breathing, respiratory failure and death.[7]

References[edit]

  1. ^ "Sophora flavescens". Natural Resources Conservation Service PLANTS Database. USDA. Retrieved 21 November 2015.
  2. ^ Krishna, Panthati Murali; Knv, Rao; S, Sandhya; Banji, David (2012). "A review on phytochemical, ethnomedical and pharmacological studies on genus Sophora, Fabaceae". Revista Brasileira de Farmacognosia. 22 (5): 1145–1154. doi:10.1590/S0102-695X2012005000043.
  3. ^ Schwarte A 2002 Phytochemische und pharmakologische Untersuchungen der Wurzeln von Sophora flavescens,unter besonderer Berücksichtigung ihrer Wirkung auf die Leukotrien- und Prostaglandinbiosynthese Archived 14 August 2011 at the Wayback Machine
  4. ^ Cha, J.-D.; Moon, S.-E.; Kim, J.-Y.; Jung, E.-K.; Lee, Y.-S. (2009). "Antibacterial activity of sophoraflavanone G isolated from the roots of Sophora flavescens against methicillin-resistant Staphylococcus aureus". Phytotherapy Research. 23 (9): 1326–1331. doi:10.1002/ptr.2540. PMID 19288534.
  5. ^ Choi, Byung-Min; Oh, Gi-Su; Lee, Jang Won; Mok, Ji Ye; Kim, Dae Keun; Jeong, Seung-Il; Jang, Seon Il (2010). "Prenylated chalcone from Sophora flavescens suppresses Th2 chemokine expression induced by cytokines via heme oxygenase-1 in human keratinocytes". Archives of Pharmacal Research. 33 (5): 753–760. doi:10.1007/s12272-010-0515-8. PMID 20512474.
  6. ^ Liu, G.; Dong, J.; Wang, H.; Hashi, Y.; Chen, S. (2011). "Characterization of alkaloids in Sophora flavescens Ait. by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry". Journal of Pharmaceutical and Biomedical Analysis. 54 (5): 1065–1072. doi:10.1016/j.jpba.2010.12.024. PMID 21227622.
  7. ^ Bensky, Dan; Clavey, Steven; Stöger, Erich; Lai Bensky, Lilian (2015). Chinese Herbal Medicine: Materia Medica (Portable 3rd ed.). Seattle, USA: Eastland Press. pp. 575–578. ISBN 978-0-939616-82-4.

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