This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-sorbitol-6-phosphate:NAD+ 2-oxidoreductase. Other names in common use include ketosephosphate reductase, ketosephosphate reductase, D-sorbitol 6-phosphate dehydrogenase, D-sorbitol-6-phosphate dehydrogenase, sorbitol-6-P-dehydrogenase, and D-glucitol-6-phosphate dehydrogenase. This enzyme participates in fructose and mannose metabolism.
Du Toit PJ, Kotze JP (1970). "The isolation and characterization of sorbitol-6-phosphate dehydrogenase from Clostridium pasteurianum". Biochim. Biophys. Acta. 206 (3): 333–42. doi:10.1016/0005-2744(70)90150-6. PMID4318899.
Liss M, Horwitz SB, Kaplan NO (1962). "D-Mannitol 1-phosphate dehydrogenase and D-sorbitol 6-phosphate dehydrogenase in Aerobacter aerogenes". J. Biol. Chem. 237: 1342–50. PMID14465816.