Sp7 transcription factor

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Sp7 transcription factor
Symbols SP7 ; OI11; OI12; OSX; osterix
External IDs OMIM606633 MGI2153568 HomoloGene15607 GeneCards: SP7 Gene
RNA expression pattern
PBB GE SP7 gnf1h02764 s at tn.png
More reference expression data
Species Human Mouse
Entrez 121340 170574
Ensembl ENSG00000170374 ENSMUSG00000060284
UniProt Q8TDD2 Q8VI67
RefSeq (mRNA) NM_001173467 NM_130458
RefSeq (protein) NP_001166938 NP_569725
Location (UCSC) Chr 12:
53.33 – 53.35 Mb
Chr 15:
102.36 – 102.37 Mb
PubMed search [1] [2]

Transcription factor Sp7 is a protein that in humans is encoded by the SP7 gene.[1][2]

SP7 is a C2H2-type zinc finger transcription factor of the SP gene family and a putative master regulator of osteoblast differentiation (Gao et al., 2004).[supplied by OMIM][2]


  1. ^ Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B (Jan 2002). "The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation". Cell 108 (1): 17–29. doi:10.1016/S0092-8674(01)00622-5. PMID 11792318. 
  2. ^ a b "Entrez Gene: SP7 Sp7 transcription factor". 

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