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Spirou may refer to:
- Spirou (character), the eponymous main character of the comics series Spirou et Fantasio and Le Petit Spirou
- Spirou (magazine), originally Le Journal de Spirou, Belgian weekly serial comics magazine
- Spirou (video game), a video game based on the comics series
- Spirou et Fantasio, comics series published in the serial journal and in hardcover book format
- Spirou et Fantasio (comic book), a 1948 comic book that precedes the official Spirou et Fantasio series
- Spirou et Fantasio (1993 TV series), 1993 animated series
- Spirou et Fantasio (2006 TV series), 2006 animated series
- Spirou Charleroi, Belgian professional basketball club
- Spiroudome, indoor arena in Charleroi, Belgium
| disambiguation page lists articles associated with the title Spirou.
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