Spondin 1

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SPON1
Protein SPON1 PDB 1szl.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases SPON1, VSGP/F-spondin, f-spondin, Spondin 1
External IDs MGI: 2385287 HomoloGene: 4453 GeneCards: SPON1
RNA expression pattern
PBB GE SPON1 209436 at fs.png

PBB GE SPON1 209437 s at fs.png

PBB GE SPON1 213993 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006108

NM_145584

RefSeq (protein)

NP_006099

NP_663559.1
NP_663559

Location (UCSC) Chr 11: 13.96 – 14.27 Mb Chr 7: 113.77 – 114.04 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Spondin-1 (also known as F-spondin) is a protein that in humans is encoded by the SPON1 gene.[3] It is secreted by cells of the floor plate and may be involved in axon guidance[4] The protein contains 807 aminoacids and is structurally composed of six thrombospondin domains, one reelin domain, and one spondin domain.


References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Apr 1999). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452. 
  4. ^ "Entrez Gene: SPON1 spondin 1, extracellular matrix protein". 

Further reading[edit]