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Histopathological image of dyshidrotic dermatitis, showing focal spongiotic change in the epidermis.

Spongiosis is mainly intercellular[1] edema (abnormal accumulation of fluid) in the epidermis,[2] and is characteristic of eczematous dermatitis, manifested clinically by intraepidermal vesicles (fluid-containing spaces), "juicy" papules, and/or lichenification.[3] It is a severe case of eczema that affects the epidermis, dermis and/or subcutaneous skin tissues.[4][5] The three types of spongiotic are acute, subacute and chronic.[5] A dermatologist can diagnose acute spongiotic by examining the skin during an office visit but a biopsy is needed for an accurate diagnosis of the type.[6]

It can be caused by several internal or external factors such as food, an insect bite, stress, medication or cosmetics. The treatment varies depending on the type and severity; it is normally treated with topical corticosteroid cream.[6]

See also[edit]


  1. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. pp. Chapter: Clinical and Pathologic Differential Diagnosis. ISBN 1-4160-2999-0.
  2. ^ Kumar, Vinay; Fausto, Nelso; Abbas, Abul (2004) Robbins & Cotran Pathologic Basis of Disease (7th ed.). Saunders. Page 1230. ISBN 0-7216-0187-1.
  3. ^ Marks, James G; Miller, Jeffery (2006). Lookingbill and Marks' Principles of Dermatology (4th ed.). Elsevier Inc. Page 28. ISBN 1-4160-3185-5.
  4. ^ Kinder, Megan. "Spongiotic Dermatitis Treatment". Dermatitis Information.
  5. ^ a b Alsaad, K O; Ghazarian, D (Dec 2005). "My Approach to Superficial Inflammatory Dermatoses". Journal of Clinical Pathology. 58.12 (2005): 1233–1241. doi:10.1136/jcp.2005.027151. PMC 1770784. PMID 16311340 – via PMC.
  6. ^ a b Jewell, Tim (March 22, 2017). "Spongiotic Dermatitis". Healthline.