Stefan Ślopek

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Stefan Ślopek
Born (1914-12-01)December 1, 1914
Skawa, Austria-Hungary
Died August 22, 1995(1995-08-22) (aged 80)
Wrocław, Poland
Nationality Polish

Stefan Ślopek was born on December 1, 1914 in Skawa near Kraków and died in Wrocław on 22 August 1995[1] and is buried in the Grabiszyński Cemetery (pl) in Wrocław. He was a Polish scientist specializing in clinical microbiology and immunology. He is the great grandson of Józef Juraszek Ślopek.

Education[edit]

After he had completed his secondary education in Tarnopol, he started his medical studies at the Faculty of Medicine in Jan Kazimierz University in Lvov, having graduated in May 1939. In 1945, upon presentation of the thesis “On modification of Lvov method of serologic examination of syphilis”, he was granted a degree of M.D. at the Faculty of Medicine of the Jagiellonian University in Kraków.

Career[edit]

In 1948, he was promoted to the rank of associate professor (docent) on the basis of a dissertation within the subject of microbiology and serology.

In 1950 he was conferred a title of professor at the Department of Microbiology of the Silesian School of Medicine where he carried on his scientific research and in 1957 got a title of full professor.

In 1965 Stefan Ślopek was elected a corresponding member of the Polish Academy of Sciences (PAN) and in 1973 as its full member.

Stefan Ślopek was an outstanding specialist in the field of clinical microbiology and immunology. Motivated by his great interest in the above-mentioned subjects, as early as before the Second World War, he started working for a branch of the State Department of Hygiene in Lvov and at the same time, under a scientific guidance of Prof. N. Gasiorowski, at the Department of Clinical Microbiology of Jan Kazimierz University in Lvov.

Slopek.mini.jpg

During World War II (1941-1945), he worked at the Institute for Research on Thyphus in Lvov with Rudolf Weigel as the head and then at its Kraków branch. At that time he was involved in production of sera, vaccines and diagnostic kits. Immediately after the war, in 1946-1949, he worked at the Faculty of Bacteriology of the Jagiellonian University and the Laboratory for Production of Sera and Vaccines of the State Department of Hygiene in Kraków.

In the years 1949-1954 he was employed at the Silesian School of Medicine as the head of the Faculty and Department of Clinical Microbiology, also fulfilling the duties of the dean of the Medical Department of the Silesian School of Medicine and from 1953 to October 1954 the rector’s duties of the above school.

During the period 1954-1973 Stefan Ślopek held the position of the head of the Faculty and Department of Clinical Microbiology of the Wrocław School of Medicine and beginning in September 1954, up to the moment of his retirement in December 1985, the director of the Ludwik Hirszfeld Institute of Immunology and Experimental Therapy of the Polish Academy of Sciences in Wrocław.

As a result of his long term efforts the new premises at 12 Czerska street were built and since 1975 have been the location of the Ludwik Hirszfeld Institute of Immunology and Experimental Therapy. The Institute is known as the centre of research in the field of immunology and experimental therapy in Poland, and owing to its wide cooperation with many foreign laboratories, it renders great service to the exploration of immunological phenomena and immunological differentiation of living organisms.

Phage therapy[edit]

The most detailed publications documenting phage therapy have come from Stefan Ślopek's group at the Institute of Immunology and Experimental Medicine of the Polish Academy of Sciences in Wroclaw.[2]

Ślopek wrote six papers on phagotherapy in which he discussed the efficiency of bacteriophages against bacterial infections including those caused by multi-resistance mutants. In one paper, Ślopek describes the effect phages had on his patients suffering from Sepsis caused by bacterial infections. Between the years 1981-1986, five hundred and fifty cases [3] were treated, all aged from 1 to 86. The treatment began with antibiotics, however, they turned out to be inefficient for five hundred and eighteen patients. Therapy began by isolating the phages to form the etiologic agents which was then administrated to the patients. The treatment could be taken either orally (phages were given 3 times a day before eating after the patient had received the necessities to neutralise gastric acids) or locally (application on wounds or cavities of a moist containing phages). Additionnaly drops of the etiologic serum could be dropped on the eyes. In case the bacterias became resistant the phages were replaced by newly selected phages.[4]

All in all, the phage therapy appears to be favorable as positive results were obtained in 508 cases (equivalent to 92.4%) and improvements were observed in 38 cases (6.9%). However, the treatment was ineffective in 4 cases (0.7%). In total, the treatment was effective for 94.2% of the patients (taking only into accounts the 518 resistant cases).[5] On the other hand, the experience had no "control" group (infected patients which were not treated with phage therapy), making the pourcentages obtained less indicative.[6]

Awards and recognitions[edit]

As a distinguished immunologist and microbiologist he held a number of responsible positions in the scientific life of Poland. From 1956 to 1987 he was editor-in-chief of the Archivum Immunologiae et Therapiae Experimentalis; in 1962-1990 – the head and president of the Coordination Committee of the interdisciplinary program “Studies and application of immunologic differentiation of organisms” member of the Presidium of its Wrocław branch; president of the Committee of Immunology; a founding member and the president of the Polish Association of Immunologist (and also its honorary member); a member of the International Union of Oncology and a member of numerous scientific societies; a member of the Presidium and the president of the Medical Sciences of the Central Qualifying Board, the vice-president of the Board, and an honorary member of the Polish Microbiological Society.

In 1981, Ślopek became a founding member of the World Cultural Council.[7]

Publications[edit]

Stefan Ślopek is the author of over 300 original scientific papers, above 30 reviewed and popularized scientific publications, 7 manuals, 7 monographs among them Immunology, Practical Immunology, Medical Microbiology (published: 1955, 1958, 1965, 1966, 1972), Clinical Microbiology, Dictionary of Immunology (published: 1980, 1983). He is also a coauthor of numerous chapters in books published in Poland and other countries.

  • Ackermann HW, Cartier C, Slopek S, Vieu JF. 1988 Morphology of Pseudomonas aeruginosa typing phages of the Lindberg set. Ann Inst Pasteur Virol. Oct-Dec;139(4):389-404.
  • Bross W, Slopek S, Slowikowski J, Mordarski M, Siedlecka M, Kozminski S. 1958 [Preoperative preparation of the large intestine.] Pol Przegl Chir. May;30(5):589-92. Polish.
  • Bross W, Slopek S, Slowikowski J, Mordarski M, Siedlecka M, Kozminski S. 1959 [New observations on sterilization of large intestinal bacterial flora.] Pol Tyg Lek (Wars). Jan 5;14(1):17-21. Polish.
  • Brzuchowska W, Godzinska H, Grzybek-Hryncewicz K, Slopek S. 1964 An attempt to identify the opsonizing factor in guinea pig serum with the immunoelectrophoretic method. Arch Immunol Ther Exp (Warsz). 12:449-54.
  • Bystricky V, Drahos V, Mulczyk M, Przondo Hessek A, Slopek S. 1964 On the structure of some bacteriophages. Acta Virol. Jul;176:369-72.
  • Dobrzanski WT, Slopek S. 1971 Achievements in microbiology in Poland in the period 1945-1970. Rev Pol Acad Sci. 16 (no. 3):28-45.
  • Durlakowa I, Lachowicz Z, Slopek S. 1967 Adhesive properties of Klebsiella bacilli. Arch Immunol Ther Exp (Warsz). 15(4):488-9.
  • Durlakowa I, Lachowicz Z, Slopek S. 1967 Biochemical properties of Klebsiella bacilli. Arch Immunol Ther Exp (Warsz). 15(4):490-6.
  • Durlakowa I, Lachowicz Z, Slopek S. 1967 Serologic characterization of Klebsiella bacilli on the basis of properties of the capsular antigens. Arch Immunol Ther Exp (Warsz). 15(4):497-504.
  • Dux K, Slopek S, Bregula U, Fogel M. 1957 [Modifications of antigenic structure of Guerin's rat epithelioma as a result of heterotransplantation on mice.] Arch Immunol Ther Exp (Warsz). 5:329-45. Polish.
  • Dux K, Slopek S, Bregula U, Fogel M. 1957 [Changes in the antigenic structure of the Guerin epithelioma during heterografting in mice.] Bull Assoc Fr Etud Cancer. Jan-Mar;44(1):72-87. French.
  • Gieldanowski J, Slopek S. 1981 Immunological activity of fractions of thymus factor X (TFX). Arch Immunol Ther Exp (Warsz). 29(2):115-9.
  • Gieldanowski J, Slopek S, Kowalczyk-Bronisz SH. 1980 Immunobiological and pharmacological properties of thymus factor X (TFX). II. Immunotropic activity. Arch Immunol Ther Exp (Warsz). 28(6):853-7.
  • Godzinska H, Osinska M, Slopek S. 1970 Immunoelectrophoretic studies on blood serum, collostrum and milk of animals of different species in their ontogenetic development. I. Immunoelectrophoretic analysis of blood serum, collostrum and milk of rabbits and sheep. Arch Immunol Ther Exp (Warsz). 18(3):305-14.
  • Godzinska H, Podolska E, Slopek S. 1970 Comparative studies on the opsonizing properties of blood serum, collostrum and milk in different species of animals in their ontogenetic development. I. Opsonizing properties of collostrum and milk of rabbits and sheep. Arch Immunol Ther Exp (Warsz). 18(3):298-304.
  • Grzybek-Hryncewicz K, Kubis K, Slopek S. 1964 The opsonizing factor in rabbit serum. Arch Immunol Ther Exp (Warsz). 12:670-5.
  • Grzybek-Hryncewicz K, Ladosz J, Slopek S. 1970 The influence of some protease inhibitors on phagocytosis. Arch Immunol Ther Exp (Warsz). 18(4):442-50.
  • Grzybek-Hryncewicz K, Ladosz J, Kubis K, Slopek S. 1964 Identification of the opsonizing factor in guinea pig serum by means of anti-opsonin. Arch Immunol Ther Exp (Warsz). 12:676-82.
  • Grzybek-Hryncewicz K, Ladosz J, Kubis-Parusel K, Slopek S. 1966 Studies on opsonins of bovine sera. I. Phagocytosis of Staphylococcus aureus (Oxford) as an outcome of the opsonizing activity of specific antibodies and inhibition by complement. Arch Immunol Ther Exp (Warsz). 14(2):147-54.
  • Grzybek-Hryncewicz K, Ladosz J, Kubis-Parusel K, Slopek S. 1966 Studies on opsonins of bovine sera. II. Phagocytosis of Shigella sonnei phase II bacilli. Arch Immunol Ther Exp (Warsz). 14(2):155-8.
  • Grzybek-Hryncewicz K, Ladosz J, Kubis-Parusel K, Slopek S. 1966 Studies on opsonins of bovine sera. 3. Factors opsonizing and inhibiting phagocytosis of Salmonella typhimurium. Arch Immunol Ther Exp (Warsz). 14(2):159-63.
  • Grzybek-Hryncewicz K, Ladosz J, Kubis K, Slopek S. 1966 Opsonizing properties of horse sera. I. Opsonization of staphylococci (Staph. aureus). Arch Immunol Ther Exp (Warsz). 14(1):15-8.
  • Grzybek-Hryncewicz K, Ladosz J, Kubis K, Slopek S. 1966 Opsonizing properties of horse sera. II. Factors stimulating phagocytosis of Shigella sonnei (phase II) bacilli. Arch Immunol Ther Exp (Warsz). 14(1):19-24.
  • Grzybek-Hryncewicz K, Ladosz J, Kubis K, Slopek S. 1966 Opsonizing properties of horse sera. 3. The role of the specific and nonspecific factors stimulating phagocytosis of Salmonella typhimurium in horse sera. Arch Immunol Ther Exp (Warsz). 14(1):25-31.
  • Grzybek-Hryncewicz K, Piotrowska I, Slopek S. 1966 Opsonizing properties of the serum of the domestic pig. I. Opsonization of Staphylococcus aureus (Oxford). Arch Immunol Ther Exp (Warsz). 14(5):543-8.
  • Grzybek-Hryncewicz K, Piotrowska I, Slopek S. 1966 Opsonizing properties of the serum of the domestic pig. II. Stimulation of phagocytosis of Shigella sonnei phase II by antibodies and inhibition by complement. Arch Immunol Ther Exp (Warsz). 14(5):549-56.
  • Grzybek-Hryncewicz K, Piotrowska I, Slopek S. 1966 Opsonizing properties of the serum of the domestic pig. 3. The role of specific antibodies and complement in the phagocytosis of Salmonella typhimurium. Arch Immunol Ther Exp (Warsz). 14(5):557-64.
  • Janowiec M, Kamienska I, Ladosz S. 1953 [T40 preparation in experimental tuberculosis.] Gruzlica. Oct;21(10):727-30. Undetermined Language.
  • Kamienska I, Venulet J, Jakimowska K, Urbanska A. 1954 [Search for new antituberculous agents.] Gruzlica. Oct;22(10):681-90. Polish.
  • Konopinska D, Kubik A, Lange A, Siemion IZ, Slopek S. 1980 Synthesis of the Gln1-facteur thymique serique and its evaluation with human E-rosette bioassay. Mol Immunol. Oct;17(10):1213-8.
  • Konopinska D, Nawrocka E, Siemion IZ, Slopek S, Szymaniec S, Klonowska E. 1977 Partial sequences of histones with tuftsin activity. Int J Pept Protein Res. Jan;9(1):71-7.
  • Konopinska D, Nawrocka E, Siemion IZ, Szymaniec S, Slopek S. 1978 Synthesis and investigation of the biological activity of tuftsin and its analogs. Arch Immunol Ther Exp (Warsz). 26(1-6):219-22.
  • Konopinska D, Nawrocka E, Siemion IZ, Szymaniec S, Slopek S. 1979 Tuftsin and its analogues. III. Modification of basic amino acid residues in the peptide chain. Arch Immunol Ther Exp (Warsz). 27(1-2):151-7.
  • Kostrzewski J, Mulczyk M, Slopek S. 1974 [Prevention of dysentery infections in human collectivities by means of polyvalent bacteriophages S. flexneri and S. sonnei] Przegl Epidemiol. 28(4):483-507. Polish.
  • Kowalewska D, Romanowska E, Slopek S, Mulczyk M. 1970 The immunologic properties of free endotoxin of Shigella sonnei. Arch Immunol Ther Exp (Warsz). 18(6):617-29.
  • Kowalewska D, Romanowska E, Slopek S. 1973 The action of free endotoxin of Shigella sonnei on the leukocytic system in rabbits. Arch Immunol Ther Exp (Warsz). 21(3):377-85.
  • Krzywy T, Durlakowa I, Kucharewicz-Krukowska A, Inglot O, Weber B. 1979 Antigenic similarity of morphologic type CIII1 bacteriophages. Arch Immunol Ther Exp (Warsz). 27(4):571-7.
  • Krzywy T, Durlakowa I, Kucharewicz-Krukowska A, Krynski S, Slopek S. 1981 Ultrastructure of bacteriophages used for typing of Staphylococcus aureus. Zentralbl Bakteriol Mikrobiol Hyg [A]. Sep;250(3):287-95.
  • Krzywy T, Durlakowa I, Slopek S, Weber B, Kucharewicz-Krukowska A. 1978 Ultrastructure and antigenic differentiation of bacteriophages of the CII and CIII morphological groups. Arch Immunol Ther Exp (Warsz). 26(1-6):571-6.
  • Krzywy T, Kucharewicz-Krukowska A, Slopek S. 1971 Evaluation of homogeneity of bacteriophages on the basis of the appearance of plaques. Arch Immunol Ther Exp (Warsz). 19(4):411-5.
  • Krzywy T, Kucharewicz-Krukowska A, Slopek S. 1971 Morphology of bacteriophages used for typing Shigella sonnei. Arch Immunol Ther Exp (Warsz). 19(1):15-45.
  • Krzywy T, Kucharewicz-Krukowska A, Slopek S. 1972 Morphology of bacteriophages of E. Hammarstrom's set for typing Shigella sonnei. Arch Immunol Ther Exp (Warsz). 20(1):73-83.
  • Krzywy T, Kucharewicz-Krukowska A, Slopek S. 1970 Morphology of bacteriophages used for typing Shigella flexneri. Arch Immunol Ther Exp (Warsz). 18(6):597-616.
  • Krzywy T, Kucharewicz-Krukowska A, Slopek S. 1976 Morphologic homogeneity of bacteriophages and their biological activity. Arch Immunol Ther Exp (Warsz). 24(1):29-37.
  • Krzywy T, Przondo-Hessek A, Slopek S. 1971 Morphology of bacteriophages used for typing Klebsiella scleromatis. Arch Immunol Ther Exp (Warsz). 19(1):1-14.
  • Krzywy T, Przondo-Hessek A, Slopek S. 1972 Morphology of bacteriophages of Klebsiella bacilli. Arch Immunol Ther Exp (Warsz). 20(1):85-107.
  • Krzywy T, Romanowska E, Slopek S. 1973 Ultrastructure of lipopolysaccharides from Shigella sonnei. Arch Immunol Ther Exp (Warsz). 21(5):685-97.
  • Krzywy T, Slopek S. 1972 Morphology of bacteriophages used for typing Shigella bacilli. Zentralbl. Bakteriol. Paasitenk. Infecktionskr. Hyg. Abt. Orig. 219:313-323.
  • Krzywy T, Slopek S. 1974 Morphology and Ultrastructure of Shigella and Klebsiella bacteriophages. Polish Medical Publishers, Warsaw.
  • Krzywy T, Slopek S, Kucharewicz-Krukowska A. 1972 Morphology of bacteriophages used for typing of Shigella bacilli. Zentralbl Bakteriol [Orig A]. Mar;219(3):313-23.
  • Kurylowicz W, Trzaska-Niedzwiecka I, Slopek S. 1950 [Types of Shigella in Poland; preliminary report.] Med Dosw Mikrobiol. 2(2):202-4. Undetermined Language.
  • Kurylowicz W, Trzaskowska-Niedzwiecka I, Slopek S. 1950 [Frequency of Shigella in suspected cases of typhoid.] Med Dosw Mikrobiol. 2(2):201-2. Undetermined Language.
  • Kucharewicz-Krukowska A, Slopek S. 1987 Immunogenic effect of bacteriophage in patients subjected to phage therapy. Arch Immunol Ther Exp (Warsz). 35(5):553-61.
  • Lahcowicz T, Slopek S. 1950 [Determination of PAS level in blood.] Med Dosw Mikrobiol. 2(2):177-8. Undetermined Language.
  • Legezynski S, Slopek S. 1949 [Studies on the effect of chemotherapy in experimental tuberculosis.] Med Dosw Mikrobiol. 1(4):611-31. Undetermined Language.
  • Legezynski S, Slopek S. 1950 [Effect of streptomycin on the course of experimental tuberculosis in the guinea pig.] Med Dosw Mikrobiol. 2(2):229. Undetermined Language.
  • Legezynski S, Slopek S. 1950 [Effect of streptomycin, PAS, salicylic acid, calciferol and nitrogranulogen on experimental tuberculosis in white mice.] Med Dosw Mikrobiol. 2(2):230. Undetermined Language.
  • Legezynski S, Slopek S. 1950 [Evaluation of Habel's method in the light of own research.] Med Dosw Mikrobiol. 2(2):305-6. Undetermined Language.
  • Maresz-Babczyszyn J, Mroz-Kurpiela E, Slopek S. 1968 Typing of Klebsiella rhinoscleromatis by means of pneumocins. Arch Immunol Ther Exp (Warsz). 16(3):406-9.
  • Milch H, Laszlo G, Slopek S, Mulczyk M. 1968 Lysotypes of Shigella flexneri. Arch Immunol Ther Exp (Warsz). 16(2):265-79.
  • Maresz-Babczyszyn J, Durlakowa I, Mroz-Kurpiela E, Lachowicz Z, Slopek S. 1967 Sensitivity of Klebsiella bacilli to bacteriocins produced by bacilli of homologous group. Arch Immunol Ther Exp (Warsz). 15(4):521-4.
  • Maresz-Babczyszyn J, Mroz-Kurpiela E, Slopek S. 1967 Sensitivity of Klebsiella bacilli to the Abbott-Shannon set of colicins. Arch Immunol Ther Exp (Warsz). 15(4):517-20.
  • Maresz-Babczyszyn J, Mroz-Kurpiela E, Slopek S. 1967 Sensitivity of Klebsiella bacilli to Fredericq's set of colicins. Arch Immunol Ther Exp (Warsz). 15(4):512-6.
  • Mikulaszek E, Slopek S, Gryzbek-Hryncewicz K, Godzinska H, Pogonowska Goldhar J. 1964 Immunochemical studies on S. sonnei bacilli. I. Effect of cell fractions of S. sonnei I, II and R upon phagocytosis. Arch Immunol Ther Exp (Warsz). 12:439-48.
  • Mulczyk M, Krukowska A, Slopek S. 1967 Typing of Shigella sonnei by colicin production. Arch Immunol Ther Exp (Warsz). 15(4):622-6.
  • Mulczyk M, Lachowicz T, Slopek S. 1963 Studies on the mechanism of variation of S. sonnei bacilli. Arch Immunol Ther Exp (Warsz). 11:105-13.
  • Mulczyk M, Slopek S. 1961 Antigenic structure of bacterio-phages used for typing S. flexneri bacilli. Arch Immunol Ther Exp (Warsz). 9:745-50.
  • Mulczyk M, Slopek S. 1971 [Role of specific bacteriophages in combating Shigella sonnei carrier state] Przegl Epidemiol. 25(4):475-6. Polish.
  • Mulczyk M, Slopek S. 1974 Use of a new phage preparation in prophylaxis and treatment of shigellosis. Acta Microbiol Acad Sci Hung. 21(1-2):115-9.
  • Mulczyk M, Slopek S, Marcinowska H. 1967 [Role of specific bacteriophage in the control of the carrier state of Shigella flexneri 6 bacilli] Przegl Epidemiol. 21(2):179-82. Polish.
  • Mulczyk M, Slopek S, Marcinowska H. 1967 Phage typing, colicin sensitivity and colicinogeny of Shigella flexneri 6. Arch Immunol Ther Exp (Warsz). 15(4):609-11.
  • Mulczyk M, Tkaczowa A, Krzywy T, Slopek S. 1967 Multiple antibiotic resistance of Shigella flexneri 6. Arch Immunol Ther Exp (Warsz). 15(4):604-8.
  • Mulczyk M, Tkaczowa A, Slopek S. 1967 Resistance of Shigella sonnei to antibiotics. Arch Immunol Ther Exp (Warsz). 15(4):630-5.
  • Nawrocka E, Siemion IZ, Slopek S, Szymaniec S. 1980 Tuftsin analogs with D-amino acid residues. Int J Pept Protein Res. Sep;16(3):200-7.
  • Pelczarska A, Romanowska E, Mulczyk M, Slopek S. 1970 Biological properties of Shigella sonnei endotoxins. Arch Immunol Ther Exp (Warsz). 18(4):451-4.
  • Przondo-Hessek A, Slopek S. 1967 Morphology and thermal sensitivity of Klebsiella bacteriophages of the collection of Przondo-Hessek. Arch Immunol Ther Exp (Warsz). 15(4):547-56.
  • Przondo-Hessek A, Slopek S. 1967 Typing of Klebsiella bacilli by means of Klebsiella bacteriophages from the collection of Przondo-Hessek. Arch Immunol Ther Exp (Warsz). 15(4):563-77.
  • Przondo-Hessek A, Slopek S. 1967 Typing of Klebsiella bacilli by means of the Klebsiella bacteriophages of the collection of Milch and Deak. Arch Immunol Ther Exp (Warsz). 15(4):578-82.
  • Przondo-Hessek A, Slopek S. 1967 Comparative studies on Klebsiella bacteriophages from the collections of milch and Deak and of Przondo-Hessek. Arch Immunol Ther Exp (Warsz). 15(4):583-8.
  • Przondo-Hessek A, Slopek S, Miodonska J. 1967 Serologic characterization of the Klebsiella bacteriophages of the Przondo-Hessek collection. Arch Immunol Ther Exp (Warsz). 15(4):557-62.
  • Przondo-Hessek A, Slopek S, Miodonska J. 1968 Phage typing of Klebsiella rhinoscleromatis. Arch Immunol Ther Exp (Warsz). 16(3):402-5.
  • Romanowska E, Pelczarska A, Wnuk W, Mulczyk M, Godzinska H, Slopek S. 1970 Isolation, purification and physico-chemical characteristic of Shigella sonnei phase I free endotoxin. Eur J Biochem. Feb;12(3):435-41.
  • Skurski A, Slopek S, Michalska E, Obst B. 1959 Studies on the mechanisms of the phagocytic reaction. II. Phagocytosis and S-R dissociation of gram-negative bacilli. J Hyg Epidemiol Microbiol Immunol. 3:389-92.
  • Slopek S. 1950 [Shigella paradysenteriae flexneri type I-III infection in the laboratory (effect of polyvalent bacteriophage on dissociation of Shigella).] Med Dosw Mikrobiol. 2(2):204-5. Undetermined Language.
  • Slopek S. 1950 [Bacteriostatic effect of streptomycin, PAS, salicylic acid, para-aminobenzoic acid, calciferol and nitrogranulogen on tuberculosis bacilli.] Med Dosw Mikrobiol. 2(2):231-2. Undetermined Language.
  • Slopek S. 1951 [Classification of dysenterial and related bacilli.] Postepy Hig Med Dosw. 59(4):80-112. Undetermined Language.
  • Slopek S. 1952 [Results of combined activities of the bacteriological laboratory and of the laboratory for synthesis of antituberculous drugs at the Institute of Tuberculosis.] Gruzlica. 20 (6 Suppl 2):92-7. Undetermined Language.
  • Slopek S. 1953 [Evaluation of microbiologic methods of diagnosis of tuberculosis.] Gruzlica. Sep;21 (9: Suppl.):3-49. Undetermined Language.
  • Slopek S. 1956 [Studies on the problem of the classification and antigenic structure of Shigella.] Ann Inst Pasteur (Paris). Dec;91 (6 Suppl):33-9. French.
  • Slopek S. 1957 [100th Anniversary of birth of the pioneer of Polish micribiology Odon Bujwid.] Postepy Hig Med Dosw. 11(4):489-90. Polish.
  • Slopek S. 1965 [Mechanism of the phenomenon of phagocytosis in the light of our studies.] Pol Arch Med Wewn. 35:291-8. Polish.
  • Slopek S. 1968 [Biology of bacterial endotoxins] Klin Oczna. 38(4):637-45. Polish.
  • Slopek S. 1969 On the 25th anniversary of the Polish People's Republic. Arch Immunol Ther Exp (Warsz). 17(5):563-4.
  • Slopek S. 1973 [Phage types of Shigella bacilli prevalent in Poland] Przegl Epidemiol. 27(2):201-5. Polish.
  • Slopek S. 1974 Thirty years of immunology in People's Poland. Arch Immunol Ther Exp (Warsz). 22(3):271-5.
  • Slopek S. 1976 [Editorial: Current views on the development and role of the immune system] Pol Arch Med Wewn. Feb;55(2):105-18. Polish.
  • Slopek S. 1976 Immunology in Poland in the years 1971-1975. Rev Pol Acad Sci. 11(3):21-34.
  • Slopek S, Dabrowski L. 1957 [E. coli strain (5444-80) having identical antigens with Shigella flexneri 3.] Arch Immunol Ther Exp (Warsz). 5:93-100. Polish.
  • Slopek S, Dabrowski L. 1957 [E. coli strain (3558-52) having identical antigens with Shigella flexneri 5 (P 119 X+).] Arch Immunol Ther Exp (Warsz). 5:101-7. Polish.
  • Slopek S, Dabrowski L. 1957 E. coli strain (5444-80) having identical antigens with S. flexneri 3. Schweiz Z Pathol Bakteriol. 20(3):330-6.
  • Slopek S, Dabrowski L. 1957 E. coli strain (3558-52) having identical antigens with S. flexneri 5 (P119 X+). Schweiz Z Pathol Bakteriol. 20(3):337-42.
  • Slopek S, Dabrowski L. 1957 [Characteristics of new antigens appearing in enteric bacteria.] Postepy Hig Med Dosw. 11(4):487-8. Polish.
  • Slopek S, Dabrowski L. 1958 Characteristics of the new thermo-labile antigens occurring in Enterobactericeae. Schweiz Z Pathol Bakteriol. 21(6):1037-43.
  • Slopek S, Dabrowski L. 1959 Studies on the thermolabile antigens of Shigella flexneri Y. Schweiz Z Pathol Bakteriol. 22(1):12-9.
  • Slopek S, Durlakowa I. 1967 Studies on the taxonomy of Klebsiella bacilli. Arch Immunol Ther Exp (Warsz). 15(4):481-7.
  • Slopek S, Durlakowa I, Jankowski S, Kucharewicz-Krukowska A, Lachowicz TM, Lachowicz Z. 1972 Variations of sensitivity of Shigella flexneri bacilli to bacteriophages as a result of recombination. Arch Immunol Ther Exp (Warsz). 20(1):61-72.
  • Slopek S, Durlakowa I, Kucharewicz-Krukowska A, Krzywy T, Slopek A, Weber B. 1972 Phage typing of Shigella flexneri. Arch Immunol Ther Exp (Warsz). 20(1):1–60.
  • Slopek S, Durlakowa I, Kucharewicz-Krukowska A, Krzywy T, Slopek A, Weber B. 1973 Phage typing of Shigella sonnei. Arch Immunol Ther Exp (Warsz). 21(1):1–161.
  • Slopek S, Durlakowa I, Weber-Dabrowska B, Dabrowski M, Kucharewicz-Krukowska A. 1984 Results of bacteriophage treatment of suppurative bacterial infections. III. Detailed evaluation of the results obtained in further 150 cases. Arch Immunol Ther Exp (Warsz). 32(3):317-35.
  • Slopek S, Gieldanowski J, Kowalczyk-Bronisz SH. 1980 Immunobiological and pharmacological properties of thymus factor X (TFX). I. Biological and pharmacological activity. Arch Immunol Ther Exp (Warsz). 28(6):827-51.
  • Slopek S, Godzinska H, Romanowska E, Mulczyk M. 1967 Antigenic structure of Shigella sonnei. I. Serologic characterization of factors which confer antigenic specificity to phase I and phase II of Shigella sonnei. Arch Immunol Ther Exp (Warsz). 15(4):612-8.
  • Slopek S, Grzybek-Hryncewicz K, Ladosz J, Kubis K. 1965 Opsonizing factors in rat serum. I. Serum components stimulating phagocytosis of Staphylococcus aureus. Arch Immunol Ther Exp (Warsz). 13(3):302-11.
  • Slopek S, Grzybek-Hryncewicz K, Ladosz J, Kubis K. 1965 Opsonizing factors in rat serum. II. Serum component taking part in the phagocytosis of S. typhimurium. Arch Immunol Ther Exp (Warsz). 13(3):312-7.
  • Slopek S, Grzybek-Hryncewicz K, Ladosz J, Kubis K. 1965 Opsonizing factors in rat serum. 3. Inhibitor and phagocytosis-stimulating factor for S. sonnei phase II bacilli. Arch Immunol Ther Exp (Warsz). 13(3):318-23.
  • Slopek S, Grzybek-Hryncewicz K, Ladosz J, Kubis K. 1965 Blocking of phagocytosis of microorganisms in guinea pig serum by means of antiopsonin. Arch Immunol Ther Exp (Warsz). 13(6):593-6.
  • Slopek S, Grzybek-Hryncewicz K, Ladosz J, Kubis-Parusel K. 1967 Opsonizing factors in human serum. II. The opsonin and inhibitor of phagocytosis of Staphylococcus aureus. Arch Immunol Ther Exp (Warsz). 15(1):18-25.
  • Slopek S, Grzybek-Hryncewicz K, Ladosz J, Kubis-Parusel K. 1967 Opsonizing factors in human serum. 3. Phagocytosis of Salmonella typhimurium. Arch Immunol Ther Exp (Warsz). 15(1):26-33.
  • Slopek S, Ladosz J, Grzybek-Hryncewicz K. 1965 An attempt to identify the components of complement in rat serum immunoelectrophoretically. Arch Immunol Ther Exp (Warsz). 13(3):324-30.
  • Slopek S, Ladosz J, Grzybek-Hryncewicz K, Kubis-Parusel K. 1967 Opsonizing factors in human serum. I. Factors inhibiting and stimulating phagocytosis of Shigella sonnei (phase II). Arch Immunol Ther Exp (Warsz). 15(1):10-7.
  • Slopek S, Ladosz J, Hryncewicz K, Brzuchowska W. 1965 A new method of identifying serum siderophilin by means of radioactive iron. Arch Immunol Ther Exp (Warsz). 13:157-60.
  • Slopek S, Ladosz J, Hryncewicz K, Brzuchowska W. 1966 New methods of identifying serum siderophilin using radioactive iron. Nature. Mar 5;209(5027):1036.
  • Slopek S, Kamienska I, Janowiec M. 1956 [Standardization of microbiological diagnosis of tuberculosis.] Postepy Hig Med Dosw. 10(4):375-8. Polish.
  • Slopek S, Kantoch M, Mulczyk M, Michalski T. 1961 Electron-microscopic observations of S. sonnei (phase I, II and R-form). Arch Immunol Ther Exp (Warsz). 9:357-61.
  • Slopek S, Krzywy T. 1985 Morphology and ultrastructure of bacteriophages. An electron microscopic study. Arch Immunol Ther Exp (Warsz). 33(1):1-217.
  • Slopek S, Krukowska A, Mulczyk M. 1968 Phage typing of Shigella sonnei. Arch Immunol Ther Exp (Warsz). 16(3):519-32.
  • Slopek S, Kucharewicz-Krukowska A, Weber-Dabrowska B, Dabrowski M. 1985 Results of bacteriophage treatment of suppurative bacterial infections. IV. Evaluation of the results obtained in 370 cases. Arch Immunol Ther Exp (Warsz). 33(2):219-40.
  • Slopek S, Kucharewicz-Krukowska A, Weber-Dabrowska B, Dabrowski M. 1985 Results of bacteriophage treatment of suppurative bacterial infections. V. Evaluation of the results obtained in children. Arch Immunol Ther Exp (Warsz). 33(2):241-59.
  • Slopek S, Kucharewicz-Krukowska A, Weber-Dabrowska B, Dabrowski M. 1985 Results of bacteriophage treatment of suppurative bacterial infections. VI. Analysis of treatment of suppurative staphylococcal infections. Arch Immunol Ther Exp (Warsz). 33(2):261-73.
  • Slopek S, Mordarska H, Mordarski M. 1958 [Method of detection of oncostatic compounds in vitro.] Postepy Hig Med Dosw. 12(2):189-90. Polish.
  • Slopek S, Mordarski M, Tkaczowa A. 1959 [Antibiotic sensitivity of bacteria isolated from patients in 1957.] Pol Tyg Lek (Wars). Mar 2;14(9):376-9. Polish.
  • Slopek S, Metzger M. 1958 Serological studies on Shigella strains isolated in Poland during 1953-1956. Schweiz Z Pathol Bakteriol. 21(1):32-53.
  • Slopek S, Metzger M, Obst B, Rudnicka I. 1957 [Serological varieties of Shigella flexneri types 1, 2, 3 & 4.] Arch Immunol Ther Exp (Warsz). 5:59-76. Polish.
  • Slopek S, Maresz-Babczyszyn J. 1967 A working scheme for typing Klebsiella bacilli by means of pneumocins. Arch Immunol Ther Exp (Warsz). 15(4):525-9.
  • Slopek S, Mulczyk M. 1967 Concerning the classification of Shigella flexneri 6 bacilli. Arch Immunol Ther Exp (Warsz). 15(4):600-3.
  • Slopek S, Mulczyk M, Krukowska A. 1967 New typing scheme of Shigella sonnei by colicin production. Arch Immunol Ther Exp (Warsz). 15(4):627-30.
  • Slopek S, Mulczyk M, Krukowska A. R 1968 Phage typing of Shigella flexneri. Arch Immunol Ther Exp (Warsz). 16(3):512-8.
  • Slopek S, Mulczyk M, Kucharewicz-Krukowska A. 1961 Antigenic structure of bacteriophages used for typing Shigella sonnei bacilli. Arch Immunol Ther Exp (Warsz). 9:751-5.
  • Slopek S, Mulczyk M, Kucharewicz-Krukowska A. 1962 [Antigen structure of bacteriophages used for typing strains of Shigella sonnei.] Arch Hyg Bakteriol. Feb;184:454-8. German.
  • Slopek S, Przondo-Hessek A, Milch H, Deak S. 1967 A working scheme for bacteriophage typing of Klebsiella bacilli. Arch Immunol Ther Exp (Warsz). 15(4):589-99.
  • Slopek S, Przondo-Hessek A, Mulczyk M. 1969 New scheme of phage typing of Shigella flexneri. Arch Roum Pathol Exp Microbiol. Dec;28(4):974-5.
  • Slopek S, Romanowska E, Gieldanowski J, Mulczyk M, Godzinska H. 1969 Free endotoxin of Shigella sonnei phase I. Bull Acad Pol Sci Biol. 17(2):81-3.
  • Slopek S, Siedlecka M, Ruczkowska J. 1957 [Sensitivity of Shigella & alkalescens-dispar strains to sulfonamides (sulfathiazole, sulfaguanidine) & antibiotics (aureomycin, chloromycetin, streptomycin).] Arch Immunol Ther Exp (Warsz). 5:271-85. Polish.
  • Slopek S, Skurski A, Lisowski J, Michalska E, OBST B. 1960 Phagocytosis of gram-negative bacteria in sera of various species. Pathol Microbiol (Basel). (Basel)23:297-302.
  • Slopek S, Skurski A, Michalska E, Dabrowski L. 1958 Phagocytosis and the antigenic structure of bacteria. Nature. Nov 1;182(4644):1243-5.
  • Slopek S, Skurski A, Michalska E, Dabrowski L. 1959 Studies on the mechanisms of the phagocytic reaction. I. Phagocytosis and the antigenic structure of gram-negative bacilli. J Hyg Epidemiol Microbiol Immunol. 3:382-8.
  • Slopek S, Steuden W, Kaczmarek M. 1983 Tuftsin-like activity of amino acids. Arch Immunol Ther Exp (Warsz). 31(6):915-7.
  • Slopek S, Steuden W, Kaczmarek M, Krukowska A, Durlak I. 1983 Application of bacteriophage in the phagocytic test. Arch Immunol Ther Exp (Warsz). 31(1):75-8.
  • Slopek S, Szymaniec S, Bromirska J. 1978 Evaluation of biological activity of TFX (Polfa) a product obtained from calf thymus. Arch Immunol Ther Exp (Warsz). 26(1-6):481-2.
  • Slopek S, Tkaczowa A, Mulczyk M. 1968 Resistance of Shigella flexneri to antibiotics. Arch Immunol Ther Exp (Warsz). 16(3):354-8.
  • Slopek S, Weber-Dabrowska B, Dabrowski M, Kucharewicz-Krukowska A. 1987 Results of bacteriophage treatment of suppurative bacterial infections in the years 1981-1986. Arch Immunol Ther Exp (Warsz). 35(5):569-83.
  • Steuden W, Slopek S, Mamczar A, Kaczmarek M. 1983 Biological aspects of tuftsin activity. Arch Immunol Ther Exp (Warsz). 31(4):575-8.
  • Tkaczowa A, Durlakowa I, Slopek S. 1967 Sensitivity of Klebsiella bacilli to antibiotics. Arch Immunol Ther Exp (Warsz). 15(4):505-11.
  • Urbanski T, Belzecki C, Chechelska B, Chylinska B, Dabrowska H, Falecki H, Gurne D, Halski L, Malinowski S, Serafinowa B, Zylowski J, Slopek S, Kamienska I, Venulet J, Janowiec M, Jakimowska K, Urbanska A, Kuzniecow A. 1958 [Searching for new anti-tuberculosis drugs.] Gruzlica. Nov;26(11):889-917. Polish.
  • Urbanski T, Gurne D, Slopek S, Mordarska H, Mordarski M. 1960 Anti-neoplastic activity of tetrahydro-1, 3-oxazine derivatives. Nature. Jul 30;187:426-7.
  • Urbanski T, Hornung S, Slopek S, Venulet J. 1952 New hydroxamic acids as antitubercular agents. Nature. Nov 1;170(4331):753-4.
  • Urbanski T, Malinowski S, Skowronska-Serafinowa B, Chechelska B, Dabrowska H, Falecki J, Gurne D, Halski L, Slopek S, Kamienska I, Venulet J, Jakimowska K, Urbanska A. 1954 [Search for new antituberculous agents.] Gruzlica. Oct;22(10):681-90. Polish.
  • Urbanski T, Serafinowa B, Malinowski S, Slopek S, Kamienska I, Venulet J, Jakimowska K. 1952 [Research on new drugs for the treatment of tuberculosis.] Gruzlica. Mar-Apr;20(2):157-70; contd. Undetermined Language.
  • Urbanski T, Serafinowa B, Malinowski S, Slopek S, Kamienska A I, Venulet J, Jakimowska K. 1952 [Research on new drugs in the treatment of tuberculosis; thiosemicarbazones.] Gruzlica. May-Jun;20(3):293-302; concl. Undetermined Language.
  • Urbanski T, Slopek S, Venulet J. 1951 Antitubercular activity of some 8-hydroxyquinoline derivatives. Nature. Jul 7;168(4262):29.
  • Weber-Dabrowska B, Dabrowski M, Slopek S. 1987 Studies on bacteriophage penetration in patients subjected to phage therapy. Arch Immunol Ther Exp (Warsz). 35(5):563-8.
  • Wlodarski K, Jakobisiak M, Slopek S. 1976 Influence of L-asparaginase on spleen colony formation in mice. Bull Acad Pol Sci Biol. 24(7):437-9.

References[edit]

  1. ^ Based on an obituary written by Marian Mordarski and Tadeusz Orlowski that appeared in http://immuno.pan.wroc.pl in October 1998.
  2. ^ Phage Therapy Laboratory at Evergreen
  3. ^ Slopek, S; Weber-Dabrowska, B; Dabrowski, M; Kucharewicz-Krukowska, A. "Results of bacteriophage treatment of suppurative bacterial infections in the years 1981-1986". Arch Immunol Ther Exp (Warsz). 35: 569–83. PMID 3455647. 
  4. ^ Sulakvelidze, A; Alavidze, Z; Morris, JG (March 2001). "Bacteriophage therapy". Antimicrob. Agents Chemother. 45: 649–59. PMC 90351Freely accessible. PMID 11181338. doi:10.1128/AAC.45.3.649-659.2001. 
  5. ^ Slopek, S; Weber-Dabrowska, B; Dabrowski, M; Kucharewicz-Krukowska, A. "Results of bacteriophage treatment of suppurative bacterial infections in the years 1981-1986". Arch Immunol Ther Exp (Warsz). 35: 569–83. PMID 3455647. 
  6. ^ Sulakvelidze, A; Alavidze, Z; Morris, JG (March 2001). "Bacteriophage therapy". Antimicrob. Agents Chemother. 45: 649–59. PMC 90351Freely accessible. PMID 11181338. doi:10.1128/AAC.45.3.649-659.2001. 
  7. ^ "About Us". World Cultural Council. Retrieved November 8, 2016.