Stein Institute for Research on Aging

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Established 1983
Director Dilip V. Jeste, M.D.
Faculty 150
Location La Jolla, California
Address 9500 Gilman Drive 0664
Stein Clinical Research Building where the Institute is housed

Sam and Rose Stein Institute for Research on Aging (Stein Institute for Research on Aging) is a premier, non-profit, multidisciplinary research institute at the University of California, San Diego School of Medicine located in La Jolla, California. Established in 1983, the Stein Institute spearheads research on successful, healthy aging through the development and application of the latest advances in biomedical and behavioral sciences.[1][2][3]

Although understanding of aging has improved enormously during the last decades, most of the prior research focused on the negative sides of aging such as age-related disability, dementia, or depression (see: ageism). The more than 150 scientists at the Stein Institute are investigating predictors and associations of successful cognitive and emotional aging. Understanding these processes requires contributions from basic sciences like neurobiology and genetics, along with the input from clinical medicine and social sciences, such as medical anthropology.


The specific focus of the Stein Institute’s research has shifted over the years since its inception in 1983. In the beginning, the primary emphasis was on Alzheimer's disease. Later, this scope was broadened to include various age-related disorders such as cancer and arthritis. Dilip V. Jeste, on assuming directorship of the Stein Institute in 2004, set the Institute’s main focus on successful aging.[1][4]


Over the past 25 years, the Stein Institute has brought together many scientists,[5] encouraged and funded research published in top scientific journals (such as JAMA),[6][7][8] supported the education of students, including medical students participating in the National Institute on Aging funded MSTAR program[1][9] and presented and broadcast about 300 public lectures on aging as part of its community outreach.[10] The number of views and downloads of the Stein lectures from UCSD-TV and UCTV, as well as YouTube and iTunes has exceeded 1.2 million views in the last couple of years.[11] The Institute's work has been cited in the media, including the BBC, New York Times, NPR, U.S. News & World Report, Huffington Post, USA Today, London Times, and Scientific American, among others.[12][13][14][15][16]

Successful Aging Evaluation (SAGE) Study[edit]

Stein Institute has developed the UCSD Successful Aging Evaluation (SAGE) Study - a unique cohort of 1,300 randomly selected people in the San Diego country, ranging in age from 50 to 99, with an oversampling of those over age 80. This longitudinal study focuses on the cognitive and emotional aspects of successful aging, including genetic information about various aspects of aging.[17][18][19][20]



  1. ^ a b "UCSD’s Stein Institute for Research on Aging Celebrates 20 Years of Exploration Into Aging Diseases". 2003. 
  2. ^ "Stein Institute". 
  3. ^ "Geriatric psychiatrists like UCSD's Dilip Jeste see a looming crisis in mental health care for elderly". Union Tribune. 2005. 
  4. ^ "American Psychiatric Association". 2012. 
  5. ^
  6. ^ Meeks, T. W.; Jeste, D. V. (2009). "Neurobiology of Wisdom: A Literature Overview". Archives of General Psychiatry. 66 (4): 355–65. PMID 19349305. doi:10.1001/archgenpsychiatry.2009.8. 
  7. ^ Jeste, D. V.; Harris, J. C. (2010). "Wisdom--A Neuroscience Perspective". JAMA: the Journal of the American Medical Association. 304 (14): 1602. doi:10.1001/jama.2010.1458. 
  8. ^
  9. ^ Dilip V. Jeste; Maureen C. Halpain; Geraldine I. Trinidad; Jennifer L. Reichstadt; Barry D. Lebowitz (2007). "UCSD’s Short-Term Research Training Programs for Trainees at Different Levels of Career Development". Academic Psychiatry. 
  10. ^
  11. ^
  12. ^ Tarkan, Laurie (2008-06-24). "Doctors Say Medication Is Overused in Dementia". The New York Times. 
  13. ^ Booth, Jenny. The Times. London  Missing or empty |title= (help)
  14. ^
  15. ^ "11 'Bad' Things We Learned May Actually Be Good For You In 2011". Huffington Post. 2011-12-12. 
  16. ^ Akitunde, Anthonia (2012-11-28). "Antipsychotic Drugs: 4 Commonly Used Meds Aren't Effective Or Safe For Older Adults, New Study Finds". The Huffington Post. 
  17. ^ "With Wisdom Comes Successful Aging". University of Southern California. 2012. 
  18. ^
  19. ^
  20. ^

External links[edit]