Stigmata (singular stigma) is a term used by members of the Christian faith to describe body marks, sores, or sensations of pain in locations corresponding to the crucifixion wounds of Jesus Christ, such as the hands, wrists, and feet.
The term originates from the line at the end of Saint Paul's Letter to the Galatians where he says, "I bear on my body the marks of Jesus." Stigmata is the plural of the Greek word στίγμα stigma, meaning a mark, tattoo, or brand such as might have been used for identification of an animal or slave. An individual bearing stigmata is referred to as a stigmatic or a stigmatist.
Stigmata are primarily associated with the Roman Catholic faith. Many reported stigmatics are members of Catholic religious orders. St. Francis of Assisi was the first recorded stigmatic in Christian history. For over fifty years, St. Padre Pio of Pietrelcina of the Order of Friars Minor Capuchin reported stigmata which were studied by several 20th-century physicians.
A high percentage (perhaps over 80%) of all stigmatics are women. In his Stigmata: A Medieval Phenomenon in a Modern Age, Edward Harrison suggests that there is no single mechanism whereby the marks of stigmata were produced.
Reported cases of stigmata take various forms. Many show some or all of five Holy Wounds that were, according to the Bible, inflicted on Jesus during his crucifixion: wounds in the wrists and feet, from nails; and in the side, from a lance. Some stigmatics display wounds to the forehead similar to those caused by the Crown of Thorns. Stigmata as crown of thorns appearing in the 20th century, e.g. on Marie Rose Ferron, have been repeatedly photographed. Other reported forms include tears of blood or sweating blood, and wounds to the back as from scourging.
Many stigmata show recurring bleeding that stops and then starts, at times after receiving Holy Communion, and a large percentage of stigmatics have shown a high desire to receive Holy Communion frequently. A relatively high percentage of stigmatics also exhibit inedia, claiming to live with minimal (or no) food or water for long periods of time, except for the Holy Eucharist. Some exhibit weight loss, and closer investigation often reveals evidence of fakery. 
Some stigmatics claim to feel the pain of wounds with no external marks; these are referred to as "invisible stigmata". Some stigmatics' wounds do not appear to clot, and seem to stay fresh and uninfected. The blood from the wounds is said, in some cases, to have a pleasant, perfumed odor, known as the Odour of Sanctity.
Individuals who have obtained the stigmata are many times described as ecstatics, overwhelmed with emotions upon receiving the stigmata. No case of stigmata is known to have occurred before the thirteenth century.
In his paper Hospitality and Pain, Christian theologian Ivan Illich states: "Compassion with Christ... is faith so strong and so deeply incarnate that it leads to the individual embodiment of the contemplated pain." His thesis is that stigmata result from exceptional poignancy of religious faith and desire to associate oneself with the suffering Messiah.
St. Francis of Assisi
St. Francis of Assisi is the first recorded stigmatic in Christian history. In 1224, two years before his death, he embarked on a journey to Mount La Verna for a forty-day fast. One morning near the feast of the Exaltation of the Cross, a six-winged angel allegedly appeared to Francis while he prayed. As the angel approached, Francis could see that the angel was crucified. He was humbled by the sight, and his heart was filled with elation joined by pain and suffering. When the angel departed, Francis was purportedly left with wounds in his hands, feet, and side as if caused by the same lance that pierced Christ’s side. The image of nails immediately appeared in his hands and feet, and the wound in his side often seeped blood. In traditional artistic depictions of the incident, Francis is accompanied by a Franciscan brother. 
St. Francis' first biographer, Thomas of Celano, reports the event as follows in his 1230 First Life of St. Francis:
"When the blessed servant of God saw these things he was filled with wonder, but he did not know what the vision meant. He rejoiced greatly in the benign and gracious expression with which he saw himself regarded by the seraph, whose beauty was indescribable; yet he was alarmed by the fact that the seraph was affixed to the cross and was suffering terribly. Thus Francis rose, one might say, sad and happy, joy and grief alternating in him. He wondered anxiously what this vision could mean, and his soul was uneasy as it searched for understanding. And as his understanding sought in vain for an explanation and his heart was filled with perplexity at the great novelty of this vision, the marks of nails began to appear in his hands and feet, just as he had seen them slightly earlier in the crucified man above him.
His wrists and feet seemed to be pierced by nails, with the heads of the nails appearing on his wrists and on the upper sides of his feet, the points appearing on the other side. The marks were round on the palm of each hand but elongated on the other side, and small pieces of flesh jutting out from the rest took on the appearance of the nail-ends, bent and driven back. In the same way the marks of nails were impressed on his feet and projected beyond the rest of the flesh. Moreover, his right side had a large wound as if it had been pierced with a spear, and it often bled so that his tunic and trousers were soaked with his sacred blood." 
St. Pio of Pietrelcina
For over fifty years, Padre Pio of Pietrelcina reported stigmata which were studied by several 20th-century physicians, whose independence from the Church is not known.  The observations were reportedly inexplicable and the wounds never became infected. His wounds healed once, but reappeared.
The wounds were examined by Luigi Romanelli, chief physician of the City Hospital of Barletta, for about one year. Dr. Giorgio Festa, a private practitioner, also examined them in 1920 and 1925. Professor Giuseppe Bastianelli, physician to Pope Benedict XV, agreed that the wounds existed, but made no other comment. Pathologist Dr. Amico Bignami of the University of Rome also observed the wounds, but could make no diagnosis. Both Bignami and Dr. Giuseppe Sala commented on the unusually smooth edges of the wounds and lack of edema.
Some modern research has indicated stigmata are of hysterical origin, or linked to dissociative identity disorders, especially the link between dietary constriction by self-starvation, dissociative mental states and self-mutilation, in the context of a religious belief. Anorexia nervosa cases often display self-mutilation similar to stigmata as part of a ritualistic, obsessive–compulsive disorder. A relationship between starvation and self-mutilation has been reported amongst prisoners of war and during famines. A psychoanalytic study of stigmatic Therese Neumann has suggested that her stigmata resulted from post-traumatic stress symptoms expressed in unconscious self-mutilation through abnormal autosuggestibility.
In his Stigmata: A Medieval Phenomenon in a Modern Age, Edward Harrison suggests that there is no single mechanism whereby the marks of stigmata were produced. Harrison found no evidence from a study of contemporary cases that the marks were supernatural in origin. He concluded, however, that marks of natural origin need not be hoaxes. Some stigmatics marked themselves in attempt to suffer with Christ as a form of piety. Others marked themselves accidentally and their marks were noted as stigmata by witnesses. Often marks of human origin produced profound and genuine religious responses.
Harrison also noted that the male-to-female ratio of stigmatics, which for many centuries had been of the order of 7 to 1, had changed over the last 100 years to a ratio of 5:4. Appearance of stigmata frequently coincided with times when issues of authority loomed large in the Church. What was significant about stigmatics was not that they were predominantly men, but that they were non-ordained. Having stigmata gave them direct access to the body of Christ without requiring the permission of the Church through the Eucharist. Only in the last century have priests been stigmatized.
From the records of St. Francis' physical ailments and symptoms, Dr. Edward Hartung concluded in 1935 that he knew what health problems plagued the holy man. Hartung believed that he had an eye ailment known as trachoma, but also had quartan malaria. Quartan malaria infects the liver, spleen, and stomach, causing the victim intense pain. One complication of quartan malaria occasionally seen around Francis' time is known as purpura, a purple hemorrhage of blood into the skin. Purpuras usually occur symmetrically, so each hand and foot would have been affected equally. If this were the case for St. Francis, he would have been afflicted by ecchymoses, an exceedingly large purpura. The purple spots of blood may have been punctured while in the wilderness and therefore appear as an open wound like that of Christ. 
Among the Warao of the Orinoco Delta, a contemplator of tutelary spirits may mystically induce the development of "openings in the palms of his hands." That these tutelary spirits are presented by the "itiriti snake" makes for a close analogue with the Seraph who endowed Francis of Assisi with his stigmata.
- Saint Paul the Apostle
- Lucia Brocadelli of Narni
- Catherine of Ricci
- Catherine of Siena
- Blessed Anne Catherine Emmerich
- Saint Francis of Assisi
- Gemma Galgani
- Saint Veronica Giuliani
- John of God
- Mary Faustina Kowalska
- Marie of the Incarnation
- Marie Rose Ferron
- Marcelline Pauper
- Marthe Robin
- Therese Neumann
- Pio of Pietrelcina
- Saint Rita of Cascia
- Zlatko Sudac
- Natuzza Evolo
- Maria Esperanza de Bianchini
- Maria Theresa Chiramel
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