Streptococcus parasanguinis

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Streptococcus parasanguinis
Scientific classification
Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Streptococcaceae
Genus: Streptococcus
Species: S. parasanguinis

Streptococcus parasanguinis is a gram-positive bacterium of the genus Streptococcus that is classified as a member of the Streptococcus viridans group. S. parasanguinis is one of the major early colonizers of dental surfaces in the human oral cavity.[1] Cell surface structures including pili and fimbriae allow the bacteria to adhere to oral surfaces. These adhesion molecules also play an important role in biofilm formation and promote aggregation with late tooth colonizers to form dental plaque.[2] The presence of S. parasanguinis in the oral cavity is associated with a healthy microflora.[3]


  1. ^ Peng Z, Fives-Taylor P, Ruiz T, et al. (2008). "Identification of critical residues in Gap3 of Streptococcus parasanguinis involved in Fap1 glycosylation, fimbrial formation and in vitro adhesion". BMC Microbiol. 8: 52. doi:10.1186/1471-2180-8-52. PMC 2335109Freely accessible. PMID 18371226. 
  2. ^ Kolenbrander, Paul E.; Robert J. Palmer Jr; Alexander H. Rickard; Nicholas S. Jakubovics; Natalia I. Chalmers; Patricia I. Diaz (23 August 2006). "Bacteria interactions and successions during plaque development". Periodontology 2000. 42 (1): 47–49. doi:10.1111/j.1600-0757.2006.00187.x. 
  3. ^ Corby, P. M.; J. Lyons-Weiler; W.A. Bretz; T.C. Hart; J.A. Aas; T. Bourmenna (November 2005). "Microbial Risk Indicators of Early Childhood Caries". Journal of Clinical Microbiology. 43 (11): 5753–5759. doi:10.1128/JCM.43.11.5753-5759.2005. PMC 1287835Freely accessible. PMID 16272513. 

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