Streptococcus tigurinus

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Streptococcus tigurinus
Scientific classification
Kingdom: Bacteria
Phylum: Firmicutes
Class: Coccus
Order: Lactobacillales
Family: Streptococcaceae
Genus: Streptococcus
Species: S. tigurinus

Streptococcus tigurinus is a novel member of the genus Streptococcus that was first discovered in 2012 by Swedish researchers.[1]

Identification[edit]

Streptococcus tigrinus is a member of the Gram-positive bacteria family Streptococcaceae and is identifiable by its 16S ribosomal RNA gene analysis.[2] S. tigurinus was initially difficult to study due to its similarity to other bacteria causing it to go unnoticed,[citation needed] but it has recently been identified as being the most structurally related to Streptococcus mitis, Streptococcus pneumoniae, Streptococcus pseudopneumoniae, Streptococcus oralis, and Streptococcus intermedius .[2]

Pathogenesis[edit]

Streptococcus tigurinus is generally not a normal part of the human bacteria flora and it is currently unknown where its natural habitat is or its potential for colonization.[3] Capable of causing serious infections if it manages to enter the body's bloodstream, usually through open wounds in the mouth, it was first discovered to cause invasive infections after it was isolated from a patient with infective endocarditis.[citation needed] It was later detected in the blood and cerebrospinal fluid of 14 other patients with varying types of serious invasive infections such as spondylodiscitis, bacteremia, meningitis, and empyema.

Treatment[edit]

As S. tigurinus is relatively rare scientists are still researching the most effective ways to combat the bacteria with some strains showing resistance to drugs like tetracycline[3] and an enhanced resistance to phagocytosis by macrophages.[4]

References[edit]

  1. ^ Krzyściak, W; Pluskwa, KK; Jurczak, A; Kościelniak, D (2013). "The pathogenicity of the Streptococcus genus". Eur. J. Clin. Microbiol. Infect. Dis. 32: 1361–76. doi:10.1007/s10096-013-1914-9. PMC 3824240Freely accessible. PMID 24141975. 
  2. ^ a b Zbinden A, et al. "Streptococcus tigurinus, a Novel Member of the Streptococcus mitis Group, Causes Invasive Infections". J Clin Microbiol. 50: 2969–73. doi:10.1128/JCM.00849-12. PMC 3421813Freely accessible. PMID 22760039. 
  3. ^ a b "Streptcococcus tigurinus". Ccos.ch. Retrieved 15 November 2014. 
  4. ^ Veloso TR, et al. "Streptococcus tigurinus is highly virulent in a rat model of experimental endocarditis". Int J Med Microbiol. 303: 498–504. doi:10.1016/j.ijmm.2013.06.006. PMID 23856340. 

External links[edit]